77837-45-7

Basic information

• Product Name: 4-AMINO-N-(3-MORPHOLIN-4-YLPROPYL)BENZENESULFONAMIDE
• Synonyms: 4-Amino-N-[3-(morpholin-4-yl)propyl]benzene-1-sulfonamide
• CAS NO: 77837-45-7
• Molecular Formula: C₁₃H₂₁N₃O₃S
• Molecular Weight: 0
• Mol File: 77837-45-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 497.4°C at 760 mmHg
• Flash Point: 254.6°C
• Appearance: /
• Vapor Pressure: 4.96E-10mmHg at 25°C
• CAS DataBase Reference: 4-AMINO-N-(3-MORPHOLIN-4-YLPROPYL)BENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-N-(3-MORPHOLIN-4-YLPROPYL)BENZENESULFONAMIDE(77837-45-7)
• EPA Substance Registry System: 4-AMINO-N-(3-MORPHOLIN-4-YLPROPYL)BENZENESULFONAMIDE(77837-45-7)

Safety Data

• Hazardous Substances Data: 77837-45-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H21N3O3S/c14-12-2-4-13(5-3-12)20(17,18)15-6-1-7-16-8-10-19-11-9-16/h2-5,15H,1,6-11,14H2/p+1

Upstream product

• 123-00-2 4-(3-Aminopropyl)morpholine 
• 121-60-8 p-acetylaminobenzenesulfonyl chloride 
• 4542-47-6 3-Morpholin-4-yl-propionitrile 
• 77283-38-6 N-acetyl-sulfanilic acid-(3-morpholino-propylamide) 

Relevant articles and documents

SUBSITUTED SULPHONAMIDES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITION COMPRISING THEREOF AND THEIR USE

Substituted sulphonamides having the general formula (I) and salts, hydrates and solvates thereof were prepared and described, wherein R1 isCO or SO2 and R2 is NH or O and where R represents linear or cyclic aliphatic chain and n represents number of linking aliphatic chain carbons (n can be 0, 1, 2 or 3), which are useful in the manufacture of the medicaments due to the carboanhydrase inhibition. These compounds are prepared by nucleophilic reaction of an amine with 4-sulfamoylbenzenesulphonyl chloride in the presence of triethylamine excess in tetrahydrofurane or in ether at temperature 0 to 20 °C. The compounds show an antiglaucomatic activity.