77837-79-7Relevant academic research and scientific papers
Divergent regioselectivity in the synthesis of trisubstituted allylic alcohols by nickel- and ruthenium-catalyzed alkyne hydrohydroxymethylation with formaldehyde
Bausch, Cory C.,Patman, Ryan L.,Breit, Bernhard,Krische, Michael J.
supporting information; experimental part, p. 5687 - 5690 (2011/08/06)
Stoichiometric metals banned: Nonsymmetrically disubstituted alkynes were converted into primary trisubstituted allylic alcohols upon exposure to paraformaldehyde in the presence of nickel or ruthenium catalysts, which exhibit complementary regioselectivity and complete stereoselectivity in the absence of exogenous reducing agents (see scheme). Copyright
