77856-53-2

Basic information

• Product Name: (S)-3-Aminoglutaricacidmonomethylester
• Synonyms: (S)-3-Aminoglutaricacidmonomethylester
• CAS NO: 77856-53-2
• Molecular Formula: C6H11 N O4
• Molecular Weight: 161.16
• Mol File: 77856-53-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 326.8±37.0 °C(Predicted)
• Appearance: /
• Density: 1.242±0.06 g/cm3(Predicted)
• PKA: 3?+-.0.10(Predicted)
• CAS DataBase Reference: (S)-3-Aminoglutaricacidmonomethylester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-Aminoglutaricacidmonomethylester(77856-53-2)
• EPA Substance Registry System: (S)-3-Aminoglutaricacidmonomethylester(77856-53-2)

Safety Data

• Hazardous Substances Data: 77856-53-2(Hazardous Substances Data)

Usage

General Description

(S)-3-Aminoglutaricacidmonomethylester is a chemical compound that consists of a glutaric acid molecule with an amino group and a methyl ester group attached to the third carbon atom. It is a chiral compound, meaning it has a non-superimposable mirror image, and the (S)-enantiomer is the specific optical isomer being referred to. (S)-3-Aminoglutaricacidmonomethylester has various potential applications in organic synthesis, drug development, and biochemical research. Additionally, it may also have potential use as a chiral building block in the preparation of pharmaceuticals and other biologically active compounds. Overall, (S)-3-Aminoglutaricacidmonomethylester is a versatile chemical with important implications in multiple fields of science and industry.

Upstream product

• 77856-51-0 dimethyl β-<(benzyloxycarbonyl)amino>glutarate 
• 77313-09-8 3-aminoglutaric acid dimethyl ester 
• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 115026-41-0 β-methyl N-benzyloxycarbonyl-(R)-aspartyl diazo ketone 
• 80974-45-4 benzyl (S)-3-N-benzyloxycarbonylamino-4-methoxycarbonylbutyrate 
• 77856-52-1 (S)-3-<(benzyloxycarbonyl)amino>-4-(methoxycarbonyl)butyric acid 

Downstream Products

• 318466-98-7 (3S,5Z)-3-[{3-[(5-bromopentyl)(2-nitrobenzenesulfonyl)amino]propyl}(2-nitrobenzenesulfonyl)amino]tetradec-5-enoic acid [3-(2-nitrobenzenesulfonylamino)propyl]amide 
• 318466-99-8 (8S,2Z)-1,9,13-tris(2-nitrobenzenesulfonyl)-8-(undec-2-enyl)-1,5,9,13-tetraazacyclooctadecan-6-one 
• 1026351-15-4 C₃₉H₅₇BrN₄O₁₁S₂ 
• 318466-96-5 (3S,5Z)-3-[{3-[(5-bromopentyl)(2-nitrobenzenesulfonyl)amino]propyl}(2-nitrobenzenesulfonyl)amino]tetradec-5-enoic acid allyl ester 
• 318466-97-6 (3S,5Z)-3-[{3-[(5-bromopentyl)(2-nitrobenzenesulfonyl)amino]propyl}(2-nitrobenzenesulfonyl)amino]tetradec-5-enoic acid 
• 318466-95-4 (3S,5Z)-3-[{3-[(5-bromopentyl)(2-nitrobenzenesulfonyl)amino]propyl}(2-nitrobenzenesulfonyl)amino]tetradec-5-enoic acid methyl ester 
• 318466-94-3 (3S,5Z)-3-(2-nitrobenzenesulfonylamino)tetradec-5-enoic acid methyl ester 

Relevant articles and documents

Total synthesis of lipogrammistin-A: Efficient macrocyclization with 2-nitrobenzenesulfonamide

Total synthesis of lipogrammistin-A (1) was accomplished using a 2-nitrobenzenesulfonyl (Ns) group for both protection and activation of amines. The β-amino ester derivative 16 was synthesized from carboxylic acid 12 in six steps by way of reduction to the aldehyde and the subsequent Wittig olefination. N-Alkylation of the Ns group under Mitsunobu conditions followed by amide formation provided 20. Intramolecular alkylation of the Ns group in 20 gave the 18-membered ring 21 as the exclusive product. After removal of the Ns group, selective acylation of the two of the three amino groups with (S)-2-methylbutyric acid furnished the desired compound 1.

Stereoselective reactions. IX. Synthetic studies on optically active β-lactams. I. Chiral synthesis of carbapenam and carbapenem ring systems starting from (S)-aspartic acid

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Synthesis of (S)- and (R)-4--2-azetidinone by Chemicoenzymatic Approach

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