77856-53-2 Usage
Uses
Used in Organic Synthesis:
(S)-3-Aminoglutaricacidmonomethylester is used as a key intermediate for the synthesis of various complex organic molecules. Its unique structure allows for the development of novel chemical entities with potential applications in different industries.
Used in Drug Development:
In the pharmaceutical industry, (S)-3-Aminoglutaricacidmonomethylester is utilized as a building block for the design and synthesis of new drugs. Its chiral nature enables the creation of enantiomerically pure compounds, which is crucial for ensuring the desired therapeutic effects and minimizing potential side effects.
Used in Biochemical Research:
(S)-3-Aminoglutaricacidmonomethylester serves as an important tool in biochemical research, where it can be employed to study enzyme mechanisms, investigate metabolic pathways, and develop new bioactive molecules with potential therapeutic applications.
Used as a Chiral Building Block:
In the preparation of pharmaceuticals and other biologically active compounds, (S)-3-Aminoglutaricacidmonomethylester is used as a chiral building block. Its enantiomeric purity ensures the synthesis of target molecules with the desired stereochemistry, which is essential for their biological activity and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 77856-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,8,5 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 77856-53:
(7*7)+(6*7)+(5*8)+(4*5)+(3*6)+(2*5)+(1*3)=182
182 % 10 = 2
So 77856-53-2 is a valid CAS Registry Number.
77856-53-2Relevant academic research and scientific papers
Total synthesis of lipogrammistin-A: Efficient macrocyclization with 2-nitrobenzenesulfonamide
Fujiwara,Kan,Fukuyama
, p. 1667 - 1669 (2007/10/03)
Total synthesis of lipogrammistin-A (1) was accomplished using a 2-nitrobenzenesulfonyl (Ns) group for both protection and activation of amines. The β-amino ester derivative 16 was synthesized from carboxylic acid 12 in six steps by way of reduction to the aldehyde and the subsequent Wittig olefination. N-Alkylation of the Ns group under Mitsunobu conditions followed by amide formation provided 20. Intramolecular alkylation of the Ns group in 20 gave the 18-membered ring 21 as the exclusive product. After removal of the Ns group, selective acylation of the two of the three amino groups with (S)-2-methylbutyric acid furnished the desired compound 1.
ENANTIOSPECIFIC SYNTHESIS OF A CHIRAL CARBAPENEM PRECURSOR FROM (R)-ASPARTIC ACID
Pellicciari, Roberto,Natalini, Benedetto,Ursini, Antonella
, p. 607 - 608 (2007/10/02)
A short enantiospecific preparation of a key intermediate to carbapenem antibiotics with (R)-aspartic acid as chiral educt is described.
