778576-04-8

Basic information

• Product Name: 2-[AMINO-(4-BROMO-PHENYL)-METHYL]-NAPHTHALEN-1-OL
• Synonyms: 2-[AMINO-(4-BROMO-PHENYL)-METHYL]-NAPHTHALEN-1-OL
• CAS NO: 778576-04-8
• Molecular Formula: C17H14BrNO
• Molecular Weight: 0
• Mol File: 778576-04-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 507.9°C at 760 mmHg
• Flash Point: 261°C
• Appearance: /
• Density: 1.478g/cm³
• Vapor Pressure: 6.13E-11mmHg at 25°C
• Refractive Index: 1.707
• CAS DataBase Reference: 2-[AMINO-(4-BROMO-PHENYL)-METHYL]-NAPHTHALEN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[AMINO-(4-BROMO-PHENYL)-METHYL]-NAPHTHALEN-1-OL(778576-04-8)
• EPA Substance Registry System: 2-[AMINO-(4-BROMO-PHENYL)-METHYL]-NAPHTHALEN-1-OL(778576-04-8)

Safety Data

• Hazardous Substances Data: 778576-04-8(Hazardous Substances Data)

Usage

General Description

2-[AMINO-(4-BROMO-PHENYL)-METHYL]-NAPHTHALEN-1-OL is a chemical compound with a molecular structure containing a naphthalene ring connected to a 4-bromo-phenyl group and an amino-methyl group. The compound has a naphthol group, which consists of a hydroxyl group attached to the naphthalene ring. This chemical compound is commonly used in the synthesis of pharmaceuticals, dyes, and organic compounds. Its unique structure and functional groups make it suitable for various chemical reactions and applications in the pharmaceutical and chemical industries.

InChI:InChI=1/C17H14BrNO/c18-13-8-5-12(6-9-13)16(19)15-10-7-11-3-1-2-4-14(11)17(15)20/h1-10,16,20H,19H2

Relevant articles and documents

High-performance liquid chromatographic enantioseparation of Betti base analogs on a newly developed isopropyl carbamate-cyclofructan6-based chiral stationary phase

The direct separation of the enantiomers of 1-(α-aminoarylmethyl)-2- naphthol, 1-(α-aminoalkyl)-2-naphthol, 2-(α-aminoarylmethyl)-1- naphthol analogs, and 2-(1-amino-2-methylpropyl)-1-naphthol) was performed on a newly developed chiral stationary phase containing isopropyl carbamate-cyclofructan6 as chiral selector, with n-heptane/alcohol/ trifluoroacetic acid as mobile phase. The effects of the mobile-phase composition, the nature and concentration of the alcoholic and acidic modifiers, and the structures of the analytes on the retention and resolution were investigated. In some cases, separations were carried out at constant mobile-phase compositions in the temperature range 5-40°C. Thermodynamic parameters and Tiso values were calculated from plots of ln k′ or ln α versus 1/T. -Δ(ΔH°) ranged from 2.8 to 3.2 kJ mol-1, -Δ(ΔS°) from 7.7 to 10.1 J mol-1 K-1, and -Δ(ΔG°) from 0.2 to 0.5 kJ mol-1. It was found that the enantioseparations were enthalpy driven. The sequence of elution of the stereoisomers determined in some cases was (R) (S).