778617-77-9 Usage
General Description
The chemical (2-Oxo-2-thiophen-2-yl-ethyl)-carbamic acid tert-butyl ester, also known as TBOC-ethanolamine, is a carbamate derivative that is commonly used as a protecting group for amines in organic synthesis. It is a crystalline solid with a molecular formula of C11H15NO3S and a molecular weight of 253.31 g/mol. TBOC-ethanolamine is a versatile reagent that can be used in a variety of chemical reactions, including peptide synthesis and drug development. It is known for its stability and compatibility with a wide range of solvents, making it a valuable tool for chemists in the field of organic and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 778617-77-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,8,6,1 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 778617-77:
(8*7)+(7*7)+(6*8)+(5*6)+(4*1)+(3*7)+(2*7)+(1*7)=229
229 % 10 = 9
So 778617-77-9 is a valid CAS Registry Number.
778617-77-9Relevant articles and documents
Oxidative Deconstruction of Azetidinols to α-Amino Ketones
Allen, Lewis A. T.,Natho, Philipp,Parsons, Philip J.,Raclea, Robert-Cristian,White, Andrew J. P.
, p. 9375 - 9385 (2020/08/14)
A silver-mediated synthesis of α-amino ketones via the oxidative deconstruction of azetidinols has been developed using a readily scalable protocol with isolated yields up to 80percent. The azetidinols are easily synthesized in one step and can act as protecting groups for these pharmaceutically relevant synthons. Furthermore, mechanistic insights are presented and these data have revealed that the transformation is likely to proceed through the β-scission of an alkoxy radical, followed by oxidation and C-N cleavage of the resulting α-amido radical.
