778640-53-2

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 778640-44-1 (1S,2R,3R,6R)-2-[(4S)-3-(tert-butoxycarbonyl-2,2-dimethyloxazolidin-4-yl)methyl]-1,2-O-isopropylidene-6-(p-methoxybenzyloxy)-4-cyclohexene-1,2,3-triol 
• 778640-51-0 (2S,3S,4R)-2,3-O-isopropylidenedioxy-4-(p-methoxybenzyloxy)-5-hexenal 
• 778640-41-8 (2R,3S,4R)-2,3-O-isopropylidene-4-(p-methoxybenzyloxy)-5-hexene-1,2,3-triol 
• 778640-57-6 methyl (2S,3S,4R)-2,3-O-isopropylidenedioxy-4-(4-methoxybenzyloxy)hex-5-enoic acid 
• 778640-38-3 (2S,3S,4R)-2,3-O-isopropylidenedioxy-4-(p-methoxybenzyloxy)-5-hexenoic acid methyl ester 
• 778640-52-1 (2S,3S,4R)-2-[(4S)-3-(tert-butoxycarbonyl-2,2-dimethyloxazolidin-4-yl)methyl]-2,3-O-isopropylidenedioxy-4-(p-methoxybenzyloxy)-5-hexenal 
• 778640-43-0 (2S,3S,4R)-2-[(4S)-3-(tert-butoxycarbonyl-2,2-dimethyloxazolidin-4-yl)methyl]-2,3-O-isopropylidenedioxy-4-(p-methoxybenzyloxy)-5-hexenoic acid methyl ester 
• 778640-37-2 (3R,4R,5S,6R)-4-[(4S)-3-(tert-butoxycarbonyl-2,2-dimethyloxazolidin-4-yl)methyl]-4,5-O-isopropylidene-6-(p-methoxybenzyloxy)-1,7-octadiene-3,4,5-triol 
• 778640-42-9 (2S,3S,4R)-2-[(4R)-3-(tert-butoxycarbonyl-2,2-dimethyloxazolidin-4-yl)hydroxymethyl]-2,3-O-isopropylidenedioxy-4-(p-methoxybenzyloxy)-5-hexenoic acid methyl ester 
• 778640-58-7 (R)-4-((R)-{(4S,5S)-5-[(R)-1-(4-Methoxy-benzyloxy)-allyl]-4-methoxycarbonyl-2,2-dimethyl-[1,3]dioxolan-4-yl}-methylsulfanylthiocarboxyoxy-methyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 95715-87-0 (R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine 

Downstream Products

• 778640-35-0 (1S,2S,3R,6R)-6-(tert-butyldimethylsiloxy)-1-[(2S)-2-(tert-butoxycarbonylamino)-3-hydroxypropyl]-1,2-O-isopropylidene-3-(p-methoxybenzyloxy)-4-cyclohexene-1,2-diol 

Relevant academic research and scientific papers

Enantioselective total synthesis of (+)-scyphostatin, a potent and specific inhibitor of neutral sphingomyelinase

The total synthesis of (+)-scyphostatin, a specific and potent neutral sphingomyelinase inhibitor from a microorganism, was accomplished for the first time starting from D-arabinose and both enantiomers of methyl 3-hydroxy-2-methylpropionate. The method i

Total synthesis of (+)-scyphostatin, a potent and specific inhibitor of neutral sphingomyelinase

The five crucial steps in the first total synthesis of (+)-scyphostatin from D-arabinose involve (see picture): a) stereoselective aldol coupling to form a quaternary stereocenter, b) ring-closing metathesis (RCM) to construct the cyclohexene ring, c) Neg