778648-38-7Relevant academic research and scientific papers
Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C)
Tamamura, Hirokazu,Sigano, Dina M.,Lewin, Nancy E.,Peach, Megan L.,Nicklaus, Marc C.,Blumberg, Peter M.,Marquez, Victor E.
, p. 4858 - 4864 (2004)
The constrained glycerol backbone of DAG-lactones, when combined with highly branched alkyl chains, has engendered a series of DAG-lactone ligands capable of binding protein kinase C (PK-C) with affinities that approximate those of phorbol esters. These b
