77868-91-8

Upstream product

• 36685-42-4 (Z)-6-methoxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one 
• 31236-71-2 lysichitalexin 
• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 75158-60-0 (6-methoxy-1-benzofuran-2-yl)(4-methoxyphenyl)methanone 
• 82358-55-2 6-methoxy-2-(4-methoxybenzyl)benzofuran-3(2H)-one 

Downstream Products

• 75158-60-0 (6-methoxy-1-benzofuran-2-yl)(4-methoxyphenyl)methanone 

Relevant academic research and scientific papers

Syntheses of 2-Benzylbenzofuran Derivatives and 2-Aryl-nitrochroman Derivatives from Nitroalkene Precursors

Simple and straightforward methods for the synthesis of 2-benzylbenzofuran, 3-substituted 2-benzylbenzofuran, and 2-aryl-nitrochroman derivatives are described. Benzofurans were generated from nitroalkenes by reduction with NaBH4 followed by a Nef reaction and acid-mediated cyclization, whereas 3-substituted 2-benzylbenzofurans were prepared from nitroalkenes by reactions with Grignard reagents followed by a Nef reaction and an acid-mediated cyclization in a one-pot process. The synthesis of chromans involved a Knoevenagel condensation and the 1,4-diazabicyclo[2.2.2]octane (DABCO) assisted cyclization of β-(2-hydroxyphenyl)-nitroethanes and benzaldehydes, also in a one-pot process. Simple and convenient methods for the synthesis of 2-benzylbenzofuran, 3-substituted 2-benzylbenzofuran, and 2-aryl-nitrochroman derivatives are described.

Neoraufuracin and Ambofuracin. Two Novel 2-Benzyl-2-O-(methyl-β-D-glucopyranos-2-yl)-trans-2,3-dihydrobenzofurans. Synthesis of the Methylated Aglycone

The structures of two novel 2-benzyl-3-O-(methyl-β-D-glucopyranos-2-yl)-trans-2,3-dihydrobenzofurans are elucidated using high resolution 1H n.m.r., 13C n.m.r., and field-desorption mass spectrometry, and also by synthesis of a derivative of the aglycone moiety common to both compounds.

The Reduction of 2-Benzylidene-3(2H)-benzofuranones with Lithium Aluminium Hydride-Aluminium Chloride

The reduction of various 2-benzylidene-3(2H)-benzofuranones with lithium aluminium hydride-aluminium chloride in ether gave the corresponding 2-benzylbenzofurans in moderate yields.The reduction of 6-methoxy-2-(4-methoxybenzoyl)benzofuran also yielded 6-m