77868-91-8Relevant articles and documents
Syntheses of 2-Benzylbenzofuran Derivatives and 2-Aryl-nitrochroman Derivatives from Nitroalkene Precursors
Huang, Chia-Yu,Kuo, Chun-Wei,Kavala, Veerababurao,Yao, Ching-Fa
, p. 2720 - 2734 (2016/06/08)
Simple and straightforward methods for the synthesis of 2-benzylbenzofuran, 3-substituted 2-benzylbenzofuran, and 2-aryl-nitrochroman derivatives are described. Benzofurans were generated from nitroalkenes by reduction with NaBH4 followed by a Nef reaction and acid-mediated cyclization, whereas 3-substituted 2-benzylbenzofurans were prepared from nitroalkenes by reactions with Grignard reagents followed by a Nef reaction and an acid-mediated cyclization in a one-pot process. The synthesis of chromans involved a Knoevenagel condensation and the 1,4-diazabicyclo[2.2.2]octane (DABCO) assisted cyclization of β-(2-hydroxyphenyl)-nitroethanes and benzaldehydes, also in a one-pot process. Simple and convenient methods for the synthesis of 2-benzylbenzofuran, 3-substituted 2-benzylbenzofuran, and 2-aryl-nitrochroman derivatives are described.
The Reduction of 2-Benzylidene-3(2H)-benzofuranones with Lithium Aluminium Hydride-Aluminium Chloride
Kurosawa, Kazu,Morita, Yasuhiro
, p. 635 - 636 (2007/10/02)
The reduction of various 2-benzylidene-3(2H)-benzofuranones with lithium aluminium hydride-aluminium chloride in ether gave the corresponding 2-benzylbenzofurans in moderate yields.The reduction of 6-methoxy-2-(4-methoxybenzoyl)benzofuran also yielded 6-m