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2-deoxy-D-glucose-6-phosphate (2DG-6P) is a key intermediate in the metabolism of 2-deoxyglucose (2DG), a glucose analog. It is formed when 2DG is phosphorylated by hexokinase, the first step in glucose metabolism. 2DG-6P cannot be further metabolized in glycolysis due to the absence of a hydroxyl group at the 2nd carbon, which is essential for isomerization to fructose-6-phosphate by phosphohexose isomerase. This blockage in metabolism leads to the accumulation of 2DG-6P, which can inhibit glucose metabolism and be used in various biological and medical applications, such as studying glucose transport and metabolism, and as a tracer in positron emission tomography (PET) scans to image tumor metabolism.

779-10-2

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779-10-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 779-10-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,7 and 9 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 779-10:
(5*7)+(4*7)+(3*9)+(2*1)+(1*0)=92
92 % 10 = 2
So 779-10-2 is a valid CAS Registry Number.

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