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INTERFERON ALFA-2A is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

77907-69-8

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77907-69-8 Usage

Uses

Antineoplastic; biological response modifier.

Brand name

Roferon-A (Hoffmann-LaRoche).

Clinical Use

Interferon alfa-2a is used in the treatment of hairy cellleukemia and AIDS-related Kaposi sarcoma in selected patientsolder than 18 years of age. It is also used to treatchronic hepatitis C, and in patients with this disease, interferonalfa-2a can normalize serum alanine aminotransferase(ALT) levels, improve liver histology, and decrease viralload. The drug has a direct antiproliferative activity againsttumor cells. Modulation of the host immune response probablyplays a role in the antitumor activity of interferon alfa-2a.The interferon is supplied as a solution or as a powder forsolution.

Drug interactions

Potentially hazardous interactions with other drugs Aminophylline and theophylline: metabolism of aminophylline and theophylline reduced, consider reducing dose of aminophylline and theophylline. Antivirals: increased risk of peripheral neuropathy with telbivudine. Immunosuppressants, e.g. ciclosporin, tacrolimus, sirolimus may have an antagonistic effect

Metabolism

Alpha-interferons are totally filtered through the glomeruli and undergo rapid proteolytic degradation during tubular reabsorption, rendering a negligible reappearance of intact alfa interferon in the systemic circulation.

Check Digit Verification of cas no

The CAS Registry Mumber 77907-69-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,9,0 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 77907-69:
(7*7)+(6*7)+(5*9)+(4*0)+(3*7)+(2*6)+(1*9)=178
178 % 10 = 8
So 77907-69-8 is a valid CAS Registry Number.

77907-69-8Upstream product

77907-69-8Downstream Products

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