77915-31-2Relevant articles and documents
Neodymium-Promoted Highly Selective Carbon-Carbon Double Bond Formation of Ketones with Allyl Halides in the Presence of Diethyl Phosphite
Xie, Dengbing,Wang, Yiqiong,Yang, Bo,Zhang, Songlin
supporting information, p. 3446 - 3451 (2020/09/02)
The carbon-carbon double bond formation via neodymium-mediated Barbier-type reaction of ketones and allyl halides in the presence of diethyl phosphite is reported for the first time. The reaction is highly α-regioselective and was conveniently carried out under mild conditions in a one-pot fashion. From a synthetic point of view, a series of conjugated alkenes were obtained in moderate to good yields in this one-pot reaction with feasible reaction conditions.
Pd(0)-catalyzed cross-coupling of allyl halides with α-diazocarbonyl compounds or N-mesylhydrazones: Synthesis of 1,3-diene compounds
Wang, Kang,Chen, Shufeng,Zhang, Hang,Xu, Shuai,Ye, Fei,Zhang, Yan,Wang, Jianbo
, p. 3809 - 3820 (2016/05/09)
With palladium catalysis, allyl bromides or chlorides react with α-diazocarbonyl compounds or N-mesylhydrazones to afford 1,3-diene derivatives. The reaction represents a novel and efficient method for the synthesis of 1,3-butadiene derivatives. Mechanist
Synthesis of dienes by palladium-catalyzed couplings of tosylhydrazones with aryl and alkenyl halides
Barluenga, Jose,Tomas-Gamasa, Maria,Aznar, Fernando,Valdes, Carlos
supporting information; experimental part, p. 3235 - 3240 (2011/02/28)
Two different combinations of coupling partners can be employed for the synthesis of conjugated dienes by palladium-catalyzed cross-coupling with tosylhydrazones: α,β-unsaturated ketone and aryl halide or alkenyl halide and non-conjugated tosylhydrazone. Depending on the substrate, a vinylogous hydride elimination is responsible for the formation of the final dienes. Copyright
