779205-09-3

Basic information

• Product Name: C₁₃H₁₆O₄S
• CAS NO: 779205-09-3
• Molecular Weight: 268.334
• Mol File: 779205-09-3.mol

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₆O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₆O₄S(779205-09-3)
• EPA Substance Registry System: C₁₃H₁₆O₄S(779205-09-3)

Safety Data

• Hazardous Substances Data: 779205-09-3(Hazardous Substances Data)

Upstream product

• 32807-28-6 Methyl 4-chloroacetoacetate 
• 90953-57-4 2-methoxy-4-mercapto-toluene 

Downstream Products

• 945773-92-2 C₂₄H₂₀F₃NO₃S₂ 
• 779205-31-1 {5-Methyl-6-[5-(4-chloro-phenyl)-isoxazol-3-ylmethoxy]-benzo[b]thiophen-3-yl}-acetic acid methyl ester 
• 945774-00-5 C₂₇H₂₃F₃O₄S 

Relevant articles and documents

Synthesis and SAR of selective benzothiophene, benzofuran, and indole-based peroxisome proliferator-activated receptor δ agonists

Recent literature has suggested the benefit of selective PPARδ agonists for the treatment of atherosclerosis and other disease states associated with the metabolic syndrome. Herein we report the synthesis and structure-activity relationships of a series of novel and selective PPARδ agonists. Our search began with identification of a novel benzothiophene template which was modified by the addition of various thiazolyl, isoxazolyl, and benzyloxy-benzyl moieties. Further elucidation of the SAR led to the identification of benzofuran and indole based templates. During the course of our research, we discovered three new chemical templates with varying degrees of affinity and potency for PPARδ versus the PPARα and PPARγ subtypes.