77924-13-1Relevant academic research and scientific papers
REACTIONS OF THE N,N-DIALKYLPYRIDYLCARBOXYLIC AMIDES WITH LITHIUM AMIDES. REGIOSELECTIVE LITHIATION OF N,N-DIISOPROPYLPYRIDYLCARBOXYLIC AMIDES, A USEFUL METHOD FOR SYNTHESIS OF 2,3- AND 3,4-DISUBSTITUTED PYRIDINES
Epsztajn, Jan,Berski, Zbigniew,Brzezinski, Jacek Z.,Jozwiak, Andrzej
, p. 4739 - 4742 (2007/10/02)
The behaviour of the N,N-dimethyl-, N,N-diethyl- and N,N,-diisopropylpyridylcarboxylic amides in the reactions with Et2NLi and iPr2NLi, and a convenient way of synthesis of 2,3- and 3,4-disubstituted pyridines, by the direct lithiation of N,N-diisopropylamides leading subsequently to the ortho new C-C bonds formation, are described.
