779335-35-2Relevant academic research and scientific papers
One-pot homolytic aromatic substitutions/HWE olefinations under microwave conditions for the formation of a small oxindole library
Teichert, Antje,Jantos, Katja,Harms, Klaus,Studer, Armido
, p. 3477 - 3480 (2007/10/03)
(Chemical Equation Presented) An efficient one-pot sequence comprising a homolytic aromatic substitution followed by an ionic Horner Wadsworth-Emmons olefination for the preparation of a small library of α,β-unsaturated oxindoles is presented. Microwave-induced heating is used to conduct these reactions. The homolytic aromatic substitution is mediated by the persistent radical effect.
