779342-74-4

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 4248-19-5 tert-butyl carbazate 

Downstream Products

• 1171115-56-2 C₁₈H₁₉Br₂NO₂ 
• 1232237-89-6 tert-butyl (R)-((R)-3-acetyl-2-oxotetrahydrofuran-3-yl)(2-bromophenyl)methylcarbamate 
• 1304145-68-3 C₁₈H₂₀BrNO₅ 
• 1304145-71-8 C₁₈H₂₂BrNO₄ 
• 1367878-38-3 (S)-tert-butyl 1-(2-bromophenyl)-2-(di-tert-butoxyphosphoryl)-2-diazoethylcarbamate 
• 1393345-40-8 C₂₁H₂₃BrN₂O₄S 
• 1416708-79-6 (1R,2S)-tert-butyl 1-(2-bromophenyl)-2-nitropropylcarbamate 
• 1572518-97-8 (R)-tert-butyl (1-(2-bromophenyl)buta-2,3-dien-1-yl)carbamate 
• 1630982-13-6 (S)-3-(N-tert-butoxycarbonylamine)-3-(2-bromophenyl)propanenitrile 
• 1627615-55-7 (2R,3R)-ethyl 3-(2-bromophenyl)-3-(tert-butoxycarbonylamino)-2-methyl-2-nitropropanoate 

Relevant academic research and scientific papers

Copper(I)-Catalyzed Asymmetric Pinacolboryl Addition of N-Boc-imines Using a Chiral Sulfoxide - Phosphine Ligand

Highly efficient and enantioselective copper(I)-catalyzed pinacolboryl addition of N-Boc-imines is reported. By using a single chiral sulfoxide-(dialkyl)phosphine (SOP) ligand, both enantiomeric isomers of α-amino boronic esters were obtained through an achiral counteranion switch.

Construction of chiral quaternary carbon center via catalytic asymmetric aza-Henry reaction with α-substituted nitroacetates

The catalytic enantioselective aza-Henry reaction of N-Boc aldimines 2 and 2-nitropropionic acid ethyl ester 3 in the mixed solvents of toluene-saturated brine (10:1) was catalyzed by cinchona quaternary ammonium salts to form a new quaternary carbon center. High yields (up to 90%), and excellent enantioselectivities (up to 99% ee) and diastereoselectivity ratio (up to 22:1) were successfully obtained with mild conditions. This journal is the Partner Organisations 2014.

Asymmetric mannich reaction of malonates with aldimines using YbIII-pybox complexes supported on self-assembled organic-inorganic hybrid silica with an imidazolium framework

Yb(OTf)3/iPr-pybox (3b) immobilized on a self-assembled organic-inorganic hybrid silica with ionic liquid phase (SAILP) (Catalyst A) behaves as an efficient and recyclable catalyst in the enantioselective Mannich reaction of malonate esters wit

Highly efficient catalytic enantioselective mannich reaction of malonates with N-tert-butoxycarbonyl imines by using Yb(OTf)3/pybox catalysts at room temperature

Go Mannich! A highly efficient and enantioselective method for the direct asymmetric reaction of dibenzyl malonate with N-tert-butoxycarbonyl aldimines in the presence of Yb(OTf)3 and iPr-pybox complexes is described (see scheme; pybox=pyridine

Chiral bromine-lithium exchange catalyzed by diamines

Different classes of prochiral polyhalide compounds have been tested in a chiral bromine-lithium exchange in the presence of different diamines with enantiomeric excesses of up to 63%.