77937-75-8

Upstream product

• 77937-79-2 (2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate 
• 77937-78-1 (2S,4S)-2-phenylcarbamoyl-4-pyrrolidinyl acetate 
• 77937-76-9 (2S,4S)-4-acetoxy-1-benzyloxycarbonylproline 
• 77937-77-0 (2S,4S)-2-phenylcarbamoyl-1-benzyloxycarbonyl-4-pyrrolidinyl acetate 
• 62-53-3 aniline 
• 13504-86-4 (2S,4S)-1-benzyloxycarbonyl-4-hydroxyproline 

Relevant academic research and scientific papers

The Enantioselective Michael Addition of Thiols to Cycloalkenones by Using (2S,4S)-2-Anilinomethyl-1-ethyl-4-hydroxypyrrolidine as Chiral Catalyst

Catalytic asymmetric addition of thiols to 2-cycloalkenone was studied by using the chiral amino alcohols, derived from L-hydroxyproline or (S)-proline, as base catalysts.Detailed investigation was carried out on the effects of the structure of the cataly

HIGHLY ENANTIOSELECTIVE MICHAEL ADDITION OF THIOLS TO 2-CYCLOHEXENONE BY USING (2S,4S)-2-(ANILINOMETHYL)-1-ETHYL-4-HYDROXYPYRROLIDINE AS A CHIRAL CATALYST

Optically active 3-arylthiocyclohexanones are produced in good optical yields by treating 2-cyclohexenone with aryl thiols in the presence of (2S,4S)-2-(anilinomethyl)-1-ethyl-4-hydroxypyrrolidine as a chiral catalyst.

ASYMMETRIC SYNTHESIS BASED ON CHIRAL DIAMINES HAVING PYRROLIDINE RING

Various highly stereoselective asymmetric reactions based on chiral diamines having pyrrolidine ring are described.Some of these reactions have been successfully applied to the syntheses of natural products.