77960-19-1

Upstream product

• 98-01-1 furfural 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 77960-36-2 [2-(3,4-Dimethoxy-phenyl)-ethyl]-[1-furan-2-yl-meth-(E)-ylidene]-amine 

Downstream Products

• 161988-98-3 [2-(3,4-Dimethoxy-phenyl)-ethyl]-furan-2-ylmethyl-[(Z)-2-((R)-2-nitro-benzenesulfinyl)-vinyl]-amine 
• 943251-46-5 2-[2-(3,4-dimethoxyphenyl)ethyl]-3-oxo-2,3-dihydro-1H-isoindole-5-carboxylic acid 

Relevant academic research and scientific papers

Synthesis of advanced intermediates of lennoxamine analogues

A simple and convenient method for synthesis of advanced isoindolone intermediates of lennoxamine and analogues is described in this paper. The intramolecular Diels-Alder reaction of furan is used as a key step in this synthesis. Georg Thieme Verlag Stuttgart.

Chiral acetylenic sulfoxides in organic synthesis: Secondary amine cyclization and total synthesis of (S)-(-)-carnegine

Michael addition of secondary amines 1b-1g onto chiral acetylenic sulfoxides 2 followed by acid induced cyclization afforded structures of tetrahydroisoquinoline skeleton in high to moderate diastereoselectivity. Optical pure (S)-(-)-carnegine has been sy