77961-17-2

Basic information

• Product Name: 5-[2-(4-Chloro-phenyl)-2-methoxy-ethyl]-2-methoxy-2,4-dimethyl-2,3-dihydro-benzo[b]oxepine
• CAS NO: 77961-17-2
• Molecular Weight: 372.892
• Mol File: 77961-17-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[2-(4-Chloro-phenyl)-2-methoxy-ethyl]-2-methoxy-2,4-dimethyl-2,3-dihydro-benzo[b]oxepine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[2-(4-Chloro-phenyl)-2-methoxy-ethyl]-2-methoxy-2,4-dimethyl-2,3-dihydro-benzo[b]oxepine(77961-17-2)
• EPA Substance Registry System: 5-[2-(4-Chloro-phenyl)-2-methoxy-ethyl]-2-methoxy-2,4-dimethyl-2,3-dihydro-benzo[b]oxepine(77961-17-2)

Safety Data

• Hazardous Substances Data: 77961-17-2(Hazardous Substances Data)

Upstream product

• 3395-81-1 4-chlorobenzaldehyde dimethyl acetal 
• 71610-30-5 1,6-dimethyl-5-methylene-3,4-benzo-2-oxabicyclo<4.1.0>hept-3-ene 

Relevant articles and documents

THE ALKOXYALKYLATION OF 1,6-DIMETHYL-5-METHYLENE-3,4-BENZO-2-OXABICYCLOHEPT-3-ENE WITH ORTHOFORMATES OR ACETALS

The reactions of the methylenehomochromene (titled compound) (1) with orthoformates (2a,b) or acetals (2c-f) easily took place in the presence of anhydrous zinc chloride to give 5-alkoxyethyl-2,3-dihydro-1-benzoxepin derivatives (3a-f) in moderate to good yields.Unusually high reactivity of 1 may be due to homoaromatic stabilization in the reaction intermediate.