77970-95-7

Basic information

• Product Name: S-METHYL-S-(4-METHOXYPHENYL) SULFOXIMINE
• Synonyms: S-METHYL-S-(4-METHOXYPHENYL) SULFOXIMINE;IMINO(4-METHOXYPHENYL)METHYL-LAMBDA(6)-SULFANONE(WXC08965)
• CAS NO: 77970-95-7
• Molecular Formula: C₈H₁₁NO₂S
• Molecular Weight: 185.24344
• Mol File: 77970-95-7.mol
• Article Data: 24

Chemical Properties

• Appearance: /
• CAS DataBase Reference: S-METHYL-S-(4-METHOXYPHENYL) SULFOXIMINE(CAS DataBase Reference)
• NIST Chemistry Reference: S-METHYL-S-(4-METHOXYPHENYL) SULFOXIMINE(77970-95-7)
• EPA Substance Registry System: S-METHYL-S-(4-METHOXYPHENYL) SULFOXIMINE(77970-95-7)

Safety Data

• Hazardous Substances Data: 77970-95-7(Hazardous Substances Data)

Upstream product

• 696-63-9 4-Methoxybenzenethiol 
• 1027729-47-0 S-methyl-S-(4-methoxyphenyl)-N-[[2-(trimethylsilyl)ethyl]sulfonyl]sulfoximine 
• 1879-16-9 1-methoxy-4-methylsulfanyl-benzene 
• 946826-75-1 N-[(4-methoxyphenyl)(methyl)(oxo)-λ⁶-sulfanylidene]cyanamide 
• 946826-94-4 N-cyano-S-methyl-S-(4-methoxyphenyl)sulfilimine 
• 952022-16-1 N-(trifluoroacetyl)-S-methyl-S-(4-methoxyphenyl)sulfoximine 
• 3517-99-5 1-methoxy-4-(methylsulfinyl)benzene 

Downstream Products

• 3517-99-5 1-methoxy-4-(methylsulfinyl)benzene 
• 56410-24-3 N,N'-bis(p-toluenesulfonyl)hydroxylamine 
• 62419-04-9 bis(4-methylphenylsulfonyl)amino 4-methylbenzenesulfonate 
• 1027714-69-7 N-[1-(4-methoxy-phenyl)-methylsulfoximine]-5-phenylethynyl-nicotinamide 
• 1402061-28-2 C₁₇H₁₇NO₃S 
• 1402061-10-2 N-propargyl methyl p-methoxyphenyl sulfoximine 
• 1608153-11-2 N-(2-pyridinylphenyl)-S-methyl-S-(4-methoxyphenyl)sulfoximine 
• 1572535-66-0 N-benzoyl-S-methyl-S-(4-methoxylphenyl) sulfoximine 

Relevant articles and documents

Electrochemical Oxidative Syntheses of NH-Sulfoximines, NH-Sulfonimidamides and Dibenzothiazines via Anodically Generated Hypervalent Iodine Intermediates

Herein, we report a general method for the synthesis of NH-sulfoximines and NH-sulfonimidamides through direct electrochemical oxidative catalysis involving an iodoarene(I)/iodoarene(III) redox couple. In addition, dibenzothiazines can be synthesized from [1,1′-biaryl]-2-sulfides under standard conditions. Notably, only a catalytic amount of iodoarene is required for the generation in situ of an active hypervalent iodine catalyst, which avoids the need for an excess of a hypervalent iodine reagent relative to conventional approaches. Moreover, this protocol features broad substrate scope and wide functional group tolerance, delivering the target compounds with good-to-excellent yields even for a scale of more than 10 g.

Nickel-Catalyzed N-Arylation of NH-Sulfoximines with Aryl Halides via Paired Electrolysis

A novel strategy for the N-arylation of NH-sulfoximines has been developed by merging nickel catalysis and electrochemistry (in an undivided cell), thereby providing a practical method for the construction of sulfoximine derivatives. Paired electrolysis is employed in this protocol, so a sacrificial anode is not required. Owing to the mild reaction conditions, excellent functional group tolerance and yield are achieved. A preliminary mechanistic study indicates that the anodic oxidation of a NiII species is crucial to promote the reductive elimination of a C?N bond from the resulting NiIII species at room temperature.

Blue light-promoted radical sulfoximido-chalcogenization of aliphatic and aromatic alkenes

A transition metal-free synthesis ofN-(arylthio/seleno)ethyl sulfoxidminesviablue light-promoted radical sulfoximido-chalcogenization of aliphatic and aromatic alkenes was developed. The sulfoximidation process demonstrated high chemoselectivity and allowed a broad substrate scope, completing the sulfoximido-chalcogenization of alkenes in good yields.