77972-83-9Relevant academic research and scientific papers
A stereoselective synthetic route to 1,6-dioxaspiro[4.4]non-3-en-2-ones from cyclopropyl alkyl ketones and α-ketoesters
Yang, Yong-Hua,Shi, Min
, p. 1709 - 1712 (2006)
The SnCl4-mediated reactions of cyclopropyl alkyl ketones with α-ketoesters afford a novel method for the synthesis of 1,6-dioxaspiro[4.4]non-3-en-2-ones with high stereoselectivities in moderate to good yields. This process is a sequential reaction involving a nucleophilic ring-opening reaction of the cyclopropane by H2O, an aldol-type reaction, and a cyclic transesterification mediated by Lewis acid.
Synthesis of Some Substituted Pyrrolidines from Cyclopropyl Carbonyl Compounds
Blake, Keith W.,Gillies, Iain,Denney, Ronald C.
, p. 700 - 702 (2007/10/02)
A series of alkyl and aryl cyclopropyl carbonyl compounds, when refluxed in N-methylformamide in the presence of magnesium chloride, gave variously substituted pyrrolidines.
