77998-61-9 Usage
General Description
4-Bromo-2-(trimethylsilyl)thiophene is a chemical compound that consists of a thiophene ring with a bromine atom in the 4th position and a trimethylsilyl group attached to the 2nd carbon. 4-Bromo-2-(trimethylsilyl)thiophene is commonly used in organic synthesis as a building block for the construction of more complex molecules. The trimethylsilyl group serves as a protecting group for reactive functional groups, allowing for selective reactions at desired positions on the thiophene ring. Additionally, the bromine atom can undergo various substitution reactions to introduce other functional groups onto the thiophene ring, making it a versatile starting material for the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Additionally, the presence of the trimethylsilyl group can enhance the solubility and stability of the compound, making it easier to handle and store in a laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 77998-61-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,9,9 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 77998-61:
(7*7)+(6*7)+(5*9)+(4*9)+(3*8)+(2*6)+(1*1)=209
209 % 10 = 9
So 77998-61-9 is a valid CAS Registry Number.
77998-61-9Relevant articles and documents
Base-catalyzed halogen dance reaction and oxidative coupling sequence as a convenient method for the preparation of dihalo-bisheteroarenes
Getmanenko, Yulia A.,Tongwa, Paul,Timofeeva, Tatiana V.,Marder, Seth R.
supporting information; experimental part, p. 2136 - 2139 (2010/08/05)
Figure presented A one-pot preparation of the 2,2′-dibromo-1, 1′-bisheteroarenes 3a-d from bromo-heteroarenes utilizing the sequence of the base-catalyzed halogen dance (BCHD) reaction and CuCl2-promoted oxidative coupling of the in situ formed α-lithio-β-halo-heteroarenes 2a-d provides a convenient access to precursors for the preparation of tricyclic heteroaromatic cores. The structures of 3a,b,d, 6, and 9 were confirmed by single-crystal X-ray analysis, and dibromides 3a and 3b were used for the preparation of dithieno-[2,3-b:3′,2′-d]-pyrrole 10a and its selenophene analogue 10b, respectively.
