78000-56-3Relevant academic research and scientific papers
Chemoenzymatic synthesis of 7-deaza cyclic adenosine 5′-diphosphate ribose analogues, membrane-permeant modulators of intracellular calcium release
Zhang, Bo,Bailey, Victoria C.,Potter, Barry V. L.
, p. 1693 - 1703 (2008)
(Chemical Equation Presented) An optimized synthetic route to 7-deaza-8-bromo-cyclic adenosine 5′-diphosphate ribose (7-deaza-8-bromo-cADPR 3), an established cell-permeant, hydrolysis-resistant cyclic adenosine 5′-diphosphate ribose (cADPR) antagonist, i
Synthesis of 7-deaza-8-bromo cyclic adenosine 5′-diphosphate ribose: The first hydrolysis resistant antagonist at the cADPR receptor
Bailey, Victoria C.,Sethi, Jaswinder K.,Galione, Antony,Potter, Barry V. L.
, p. 695 - 696 (1997)
7-Deaza-8-bromo cyclic adenosine 5′-diphosphate ribose is synthesised from 7-deazaadenosine via 7-deaza-8-bromo nicotinamide adenine dinucleotide; it is both a more potent antagonist than the 8-bromo derivative and has the advantage of chemical and enzyma
Synthesis of 8-(1,2,3-triazol-1-yl)-7-deazapurine nucleosides by azide–alkyne click reactions and direct C[sbnd]H bond functionalization
Kavoosi, Sam,Rayala, Ramanjaneyulu,Walsh, Brenna,Barrios, Maria,Gonzalez, Walter G.,Miksovska, Jaroslava,Mathivathanan, Logesh,Raptis, Raphael G.,Wnuk, Stanislaw F.
supporting information, p. 4364 - 4367 (2016/09/13)
Treatment of toyocamycin or sangivamycin with 1,3-dibromo-5,5-dimethylhydantoin in MeOH (rt/30?min) gave 8-bromotoyocamycin and 8-bromosangivamycin in good yields. Nucleophilic aromatic substitution of 8-bromotoyocamycin with sodium azide provided novel 8
