78007-43-9Relevant academic research and scientific papers
Multicomponent synthesis of highly substituted imidazolines via a silicon mediated 1,3-dipolar cycloaddition
Peddibhotla,Tepe
, p. 1433 - 1440 (2007/10/03)
A diastereoselective multicomponent synthesis of highly functionalized imidazolines is reported. A silicon mediated 1,3 dipolar cycloaddition of the in situ generated münchnone with an imine resulted in the formation of highly substituted imidazolines. The imidazolines contain a four-point diversity and two stereocenters and the cycloaddition reaction is applicable to aryl, alkyl, acyl, and heterocyclic substitutions.
