78019-04-2Relevant academic research and scientific papers
Kinetics and Mechanisms of Nucleophilic Displacements with Heterocycles as Leaving Groups. Part 6. Reactions of N-(Substituted Benzyl)-azaheterocyclonium Compounds with Piperidine
Katritzky, Alan R.,Basinski, Wlodzimierz H.,Ou, Yu Xiang,Musumarra, Giuseppe,Patel, Ranjan C.
, p. 1055 - 1060 (2007/10/02)
The preparation is described of series of N-(p-substituted)benzyl and N-(2-furfuryl) compounds with different heterocyclic leaving groups.First- and second-order rate constants for their reactions with piperidine in chlorobenzene are measured and discusse
Kinetics and Mechanisms of Nucleophilic Displacements with Heterocycles as Leaving Groups. 2. N-Benzylpyridinium Cations: Rate Variation with Steric Effects in the Leaving Group
Katritzky, Alan R.,El-Mowafy, Azzahra M.,Musumarra, Giuseppe,Sakizadeh, Kumars,Sana-Ullah, Choudhry,et al.
, p. 3823 - 3830 (2007/10/02)
N-Benzyl groups are transferred to piperidine from pyridinium ions by unimolecular SN1 and/or bimolecular SN2 mechanisms.Steric acceleration by α-phenyl groups is reduced by an adjacent β-methyl group but increased by constraining th
