78025-22-6

Usage

Uses

Used in Pharmaceutical Industry:
(2-amino-4-chlorophenoxy)acetonitrile is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the creation of drugs that target specific biological pathways, potentially leading to the development of new treatments for a range of diseases.
Used in Agrochemical Industry:
In the agrochemical sector, (2-amino-4-chlorophenoxy)acetonitrile serves as a precursor in the production of pesticides and other crop protection agents. Its reactivity and functional group make it suitable for the development of compounds that can effectively control pests and enhance crop yields.
Used in Chemical Research and Development:
(2-amino-4-chlorophenoxy)acetonitrile is also employed in the research and development of new chemical entities and materials. Its properties make it a valuable tool for scientists exploring innovative applications and pushing the boundaries of chemical synthesis.
Safety Precautions:
Given the toxicological properties of (2-amino-4-chlorophenoxy)acetonitrile, it is crucial to exercise proper safety measures when handling (2-amino-4-chlorophenoxy)acetonitrile in laboratory settings. This includes the use of personal protective equipment, working in well-ventilated areas, and adhering to established safety protocols to minimize health risks.

Upstream product

• 1083419-01-5 (5-chloro-2-cyanomethoxy-phenyl)-carbamic acid tert-butyl ester 
• 892413-92-2 (5-chloro-2-hydroxy-phenyl)-carbamic acid tert-butyl ester 
• 95-85-2 2-hydroxy-5-chloro-aniline 

Downstream Products

• 1441755-68-5 4-[(5-chloro-2-cyanomethoxy-phenylamino)-(4-chloro-phenyl)-methyl]-5-isopropyl-1-(2-methoxy-phenyl)-1H-pyrazole-3-carboxylic acid 
• 1441755-60-7 {4-chloro-2-[4-(4-chloro-phenyl)-3-isopropyl-2-(2-methoxy-phenyl)-6-oxo-2,6-dihydro-4H-pyrrolo[3,4-c]pyrazol-5-yl]-phenoxy}-acetonitrile 
• 1441755-52-7 4-(4-chloro-phenyl)-5-[5-chloro-2-(2H-tetrazol-5-ylmethoxy)-phenyl]-3-isopropyl-2-(2-methoxy-phenyl)-4,5-dihydro-2H-pyrrolo[3,4-c]pyrazol-6-one 
• 1441755-76-5 4-[(5-chloro-2-cyanomethoxy-phenylamino)-(4-chloro-phenyl)-methyl]-5-isopropyl-1-(2-methoxy-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Pyrazolopyrrolidine compounds

The invention relates to compounds of formula (I) as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.

3-Oxo-5H-pyrimido[2,1-c][1,4 ]benzoxazines

3-Oxo-5H-pyrimido[2,1-c][1,4]benzoxazine derivatives, optionally substituted with a hydroxymethyl, carboxy or loweer alkoxycarbonyl at position 1 and optionally substituted at positions 8 or 9, with a lowr alkyl or halo are disclosed. The derivatives are antiallergy agents and methods for their preparation and use are given.