78038-53-6Relevant academic research and scientific papers
Synthesis, characterization, antiamoebic activity and toxicity of ferrocenyl chalcones
Mukhtar, Sayeed,Manasreh, Waleed Atef,Parveen, Humaira,Azam, Amir
, p. 8407 - 8412 (2014)
Two series of ferrocenyl chalcones were synthesized and evaluated for in vitro antiamoebic activity against HM1:IMSS strain of Entamoeba histolytica. The results showed that compounds of series B having ferrocene ring adjacent to carbonyl linkage were generally more active than compounds of series A. Compounds having unsubstituted phenyl ring, methoxy substitution, thiomethyl group, chloro group and nitro group, exhibited better antiamoebic activity than the reference drug metronidazole. The toxicological studies of these compounds on human kidney epithelial cell line showed that all compounds were non-toxic. The compound 1-ferrocenyl-3-(4-nitrophenyl)-2-propen-1- one (18) was found most active and least toxic among all compounds.
Electrochemical method in determination of antioxidative activity using ferrocene derivatives as examples
Tyurin,Meleshonkova,Dolganov,Glukhova,Milaeva
, p. 647 - 655 (2012/02/06)
Electrochemical method for the evaluation of antioxidative activity of compounds based on their reaction with the stable radical, 2,2-diphenyl-1- picrylhydrazyl, was suggested with monitoring of the reaction by cyclic voltammetry (CVA). Antioxidative prop
CYCLIC VOLTAMMETRY OF ARYLFERROCENES AND FERROCENE ANALOGUES OF CHALCONES. SUBSTITUENT EFFECTS ON THE ELECTRON DENSITY DISTRIBUTION IN FERROCENE DERIVATIVES
Nagy, Agnes G.,Toma, Stefan
, p. 257 - 268 (2007/10/02)
Cyclic voltammetry studies of arylferrocenes and two series of ferrocene analogues of chalcone are presented.Good correlations of the oxidation potentials (E1/2) with the ? Hammett constants as well as with the 13C chemical shifts for carbon atoms with different positions in the ferrocenyl moiety have been found.The different sensitivities of these series to the substituent effects is discussed.The variation of the electron density distribution at the carbon atoms of the cyclopentadienyl rings is given numerically as a function of the electron-donating or electron-withdrawing strengths of the substituents.
