78052-20-7

Basic information

• Product Name: 2,4-dichloro-5-methylquinazoline
• Synonyms: 2,4-dichloro-5-methylquinazoline
• CAS NO: 78052-20-7
• Molecular Formula: C9H6Cl2N2
• Molecular Weight: 213.066
• Mol File: 78052-20-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 292.4±33.0 °C(Predicted)
• Appearance: /
• Density: 1.418±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -0.15±0.30(Predicted)
• CAS DataBase Reference: 2,4-dichloro-5-methylquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichloro-5-methylquinazoline(78052-20-7)
• EPA Substance Registry System: 2,4-dichloro-5-methylquinazoline(78052-20-7)

Safety Data

• Hazardous Substances Data: 78052-20-7(Hazardous Substances Data)

Usage

Description

2,4-Dichloro-5-methylquinazoline is a chlorinated quinazoline derivative with the molecular formula C9H6Cl2N2. It is a chemical compound that has potential applications in pharmaceutical and agrochemical industries due to its unique chemical properties.
Used in Pharmaceutical Industry:
2,4-Dichloro-5-methylquinazoline is used as an antitumor agent for its potential anticancer activity. Its derivatives have shown promising results in inhibiting the growth of cancer cells, making it a valuable compound for the development of new cancer treatments.
Used in Agrochemical Industry:
2,4-Dichloro-5-methylquinazoline is used as a potential herbicide for its ability to inhibit plant development. Its chemical properties make it a versatile compound for controlling unwanted plant growth in agricultural settings.

Upstream product

• 52570-39-5 5-methyl-1H-quinazoline-2,4-dione 
• 4389-50-8 2-amino-6-methylbenzoic acid 

Downstream Products

• 50608-63-4 BL-3459 

Relevant articles and documents

DIACYLGLYCEROL KINASE MODULATING COMPOUNDS

The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.

BICYCLIC DERIVATIVE CONTAINING PYRIMIDINE RING, AND PREPARATION METHOD THEREFOR

The present invention provides: a bicyclic derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof; a preparation method therefor, a pharmaceutical composition comprising the same; and a use therefor. According to the present invention, the bicyclic compound derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof acts as a 5-HT4 receptor agonist, and thus can be usefully applied to the prevention or treatment of dysfunction in gastrointestinal motility, for example, gastrointestinal diseases such as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, diabetic gastric atony and the like.

PIPERIDINE SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES WITH INHIBITORY ACTIVITY ON THE REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)

The invention concerns novel substituted bicyclic pyrazolo pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further conce