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Z-pGlu-Nle-Pro-NH2 is a synthetic peptide consisting of four amino acids: Z-protected glutamic acid (Z-pGlu), norleucine (Nle), proline (Pro), and an amide group (NH2) at the C-terminus. This sequence is of interest in the field of peptide chemistry and may have potential applications in drug development, particularly in the design of peptide-based therapeutics. The Z-protecting group on the glutamic acid residue is used to prevent unwanted side reactions during peptide synthesis, ensuring that the peptide is synthesized with the correct sequence and functional groups intact. The norleucine is a non-standard amino acid that can provide unique properties to the peptide, such as altered stability or receptor binding. Proline, with its cyclic structure, can introduce kinks in the peptide backbone, affecting the overall conformation and activity of the peptide. The amide group at the C-terminus can contribute to the peptide's solubility and biological activity. Overall, Z-pGlu-Nle-Pro-NH2 is a peptide with specific structural features that may be exploited for various biomedical applications.

78057-98-4

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78057-98-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 78057-98-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,0,5 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 78057-98:
(7*7)+(6*8)+(5*0)+(4*5)+(3*7)+(2*9)+(1*8)=164
164 % 10 = 4
So 78057-98-4 is a valid CAS Registry Number.

78057-98-4Downstream Products

78057-98-4Relevant academic research and scientific papers

Synthesis of Thyrotropin-Releasing Hormone Analogues. 1. Complete Dissociation of Central Nervous Effects from Thyrotropin-Releasing Activity

Szirtes, Tamas,Kisfaludy, Lajos,Palosi, Eva,Szporny, Laszlo

, p. 741 - 745 (2007/10/02)

Twenty-four thyrotropin-releasing hormone (TRH) analogues containing mainly aliphatic amino acids in position 2 were synthesized and tested for central nervous system (CNS) and hormonal (TSH) activity.Application of the pentafluorophenyl ester method in t

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