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"Z-pGlu-Thr(Bzl)-Pro-NH2" is a peptide compound consisting of four amino acids: N-benzyloxycarbonyl-protected glutamic acid (Z-pGlu), threonine with a benzyl group (Thr(Bzl)), and proline (Pro), with an amide group at the C-terminus (NH2). This sequence is often used in peptide synthesis as a building block for larger polypeptides or proteins. The benzyl protecting groups are commonly used in organic synthesis to prevent unwanted side reactions, such as peptide bond formation, until the desired step in the synthesis is reached. Once the peptide is fully assembled, the protecting groups can be removed to reveal the active peptide. This particular sequence may have applications in pharmaceuticals, research, or as a model for studying protein structure and function.

78058-23-8

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78058-23-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 78058-23-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,0,5 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 78058-23:
(7*7)+(6*8)+(5*0)+(4*5)+(3*8)+(2*2)+(1*3)=148
148 % 10 = 8
So 78058-23-8 is a valid CAS Registry Number.

78058-23-8Downstream Products

78058-23-8Relevant academic research and scientific papers

Synthesis of Thyrotropin-Releasing Hormone Analogues. 1. Complete Dissociation of Central Nervous Effects from Thyrotropin-Releasing Activity

Szirtes, Tamas,Kisfaludy, Lajos,Palosi, Eva,Szporny, Laszlo

, p. 741 - 745 (2007/10/02)

Twenty-four thyrotropin-releasing hormone (TRH) analogues containing mainly aliphatic amino acids in position 2 were synthesized and tested for central nervous system (CNS) and hormonal (TSH) activity.Application of the pentafluorophenyl ester method in t

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