780752-73-0Relevant academic research and scientific papers
4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors
Frechette, Sylvie,Leit, Silvana,Woo, Soon Hyung,Lapointe, Guillaume,Jeannotte, Guillaume,Moradei, Oscar,Paquin, Isabelle,Bouchain, Giliane,Raeppel, Stephane,Gaudette, Frederic,Zhou, Nancy,Vaisburg, Arkadii,Fournel, Marielle,Yan, Pu Theresa,Trachy-Bourget, Marie-Claude,Kalita, Ann,Robert, Marie-France,Lu, Aihua,Rahil, Jubrail,Robert MacLeod,Besterman, Jeffrey M.,Li, Zuomei,Delorme, Daniel
, p. 1502 - 1506 (2008/09/19)
The synthesis and biological evaluation of a variety of 4-(heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs is described. Some of these compounds were shown to inhibit HDAC1 with IC50 values below the micromolar range, indu
