780772-24-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1443650-80-3 (S)-2-methyl-4-((1-phenyl-1H-tetrazol-5-yl)thio)butan-1-ol 
• 1443650-81-4 (2S)-2-methyl-4-(1-phenyl-1H-tetrazole-5-sulfonyl)butan-1-ol 
• 299430-30-1 (2R)-toluene-4-sulfonic acid 3-(tert-butyldimethylsilanyloxy)-2-methylpropyl ester 
• 204917-42-0 (3S)-4-(tert-butyldimethylsilanyloxy)-3-methylbutyraldehyde 
• 188692-78-6 (3S)-4-(tert-butyldimethylsilanyloxy)-3-methylbutyronitrile 
• 156592-93-7 (3S)-4-<(tert-butyldimethylsilyl)oxy>-3-methylbutanol 
• 105859-44-7 methyl (R)-2-methyl-3-[(tert-butyldimethylsilyl)oxy]propionate 
• 105859-45-8 (S)-3-(tert-butyldimethylsilyloxy)-2-methylpropan-1-ol 

Downstream Products

• 780772-63-6 tert-Butyl-{(4E,8E)-(2S,6R,10R,11R)-11-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecyloxy)-benzyloxy]-2,6,10-trimethyl-dodeca-4,8-dienyloxy}-dimethyl-silane 
• 780772-56-7 tert-Butyl-{(4E,8E)-(2S,6S,10R,11R)-11-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecyloxy)-benzyloxy]-2,6,10-trimethyl-dodeca-4,8-dienyloxy}-dimethyl-silane 
• 780772-62-5 tert-Butyl-dimethyl-{(4E,8E)-(2S,6R,10R,11S)-2,6,10-trimethyl-11-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-pentadecafluoro-decyloxy)-benzyloxy]-dodeca-4,8-dienyloxy}-silane 
• 780772-59-0 tert-Butyl-{(4E,8E)-(2R,6S,10R,11R)-11-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecyloxy)-benzyloxy]-2,6,10-trimethyl-dodeca-4,8-dienyloxy}-dimethyl-silane 
• 780773-25-3 (1R,2R,6S,10R)-1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl-oxy)-4-(1,2,6,10-tetramethyldodecyloxymethyl)benzene 
• 780773-21-9 (1R,2R,6R,10S)-1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl-oxy)-4-(1,2,6,10-tetramethyldodecyloxymethyl)benzene 
• 780773-90-2 (1R,2R,6R,10R)-1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl-oxy)-4-(1,2,6,10-tetramethyldodecyloxymethyl)benzene 
• 780772-58-9 tert-Butyl-dimethyl-{(4E,8E)-(2R,6S,10R,11S)-2,6,10-trimethyl-11-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-pentadecafluoro-decyloxy)-benzyloxy]-dodeca-4,8-dienyloxy}-silane 
• 780772-55-6 tert-Butyl-dimethyl-{(4E,8E)-(2S,6S,10R,11S)-2,6,10-trimethyl-11-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-pentadecafluoro-decyloxy)-benzyloxy]-dodeca-4,8-dienyloxy}-silane 
• 780773-03-7 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecyloxy)-4-((3E,7E)-(1R,2R,6R,10S)-1,2,6,10-tetramethyl-dodeca-3,7,11-trienyloxymethyl)-benzene 
• 780772-91-0 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecyloxy)-4-((3E,7E)-(1R,2R,6S,10R)-1,2,6,10-tetramethyl-dodeca-3,7,11-trienyloxymethyl)-benzene 
• 780772-79-4 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecyloxy)-4-((3E,7E)-(1R,2R,6S,10S)-1,2,6,10-tetramethyl-dodeca-3,7,11-trienyloxymethyl)-benzene 
• 780772-95-4 (4E,8E)-(2S,6R,10R,11R)-11-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecyloxy)-benzyloxy]-2,6,10-trimethyl-dodeca-4,8-dien-1-ol 
• 780772-83-0 (4E,8E)-(2R,6S,10R,11R)-11-[4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecyloxy)-benzyloxy]-2,6,10-trimethyl-dodeca-4,8-dien-1-ol 

Relevant academic research and scientific papers

Synthesis of the C6-C21 fragment of epothilone analogues

(2S,4E,6Z,9S,10E)-9-[tert-Butyl(diphenyl)silyloxymethyl]-2,6,10-trimethyl-11-(2-methylthiazol-4-yl)undeca-4,6,10-trien-1-ol, a key precursor for epothilone analogues, was prepared by multi-step synthesis using the Julia-Kocienski olefination at the key step.

Building blocks for (C15-C3)-modified epothilone D analogs

A promising potentially biologically active structure have been designed by isosteric rearrangement of the C15-C3 fragment of epothilone D, and building blocks necessary for its assembly have been synthesized.

Synthesis of all 16 stereoisomers of pinesaw fly sex pheromones - Tools and tactics for solving problems in fluorous mixture synthesis

The application of fluorous mixture synthesis (FMS) for accessing natural products and their stereoisomers was validated by the total synthesis of all 16 stereoisomers of the pine sawfly sex pheromone. Four fluorous p-methoxybenzyl groups were used as tag