780789-16-4Relevant academic research and scientific papers
Stereocontrolled synthesis of the aminocyclitol moiety of (+)-trehazolin via C-H insertion reaction of alkylidenecarbene
Akiyama, Megumi,Awamura, Toshiki,Kimura, Kazuhito,Hosomi, Yoshimi,Kobayashi, Ayako,Tsuji, Kazutaka,Kuboki, Atsuhito,Ohira, Susumu
, p. 7133 - 7136 (2004)
The aminocyclitol moiety of (+)-trehazolin, a powerful trehalase inhibitor, was synthesized in a stereocontrolled manner from cis-2-butene-1,4-diol via C-H insertion reaction of the alkylidenecarbene, followed by regioselective opening of the epoxide ring
