78080-41-8

Upstream product

• 75-08-1 ethanethiol 
• 1817-57-8 4-phenyl-3-butyne-2-one 
• 81375-98-6 4,4-bis(ethylsulfanyl)but-3-en-2-one 
• 98-80-6 phenylboronic acid 

Downstream Products

• 39092-21-2 4-phenyl-4-(p-tolyl)but-3-en-2-one 
• 1315282-99-5 C₁₆H₁₃ClO 
• 124492-08-6 C₁₇H₁₄O₂ 
• 124492-34-8 4-((E)-3-Oxo-1-phenyl-but-1-enyl)-benzaldehyde 

Relevant academic research and scientific papers

Regio- and stereoselective synthesis of multisubstituted olefins and conjugate dienes by using α-oxo ketene dithioacetals as the building blocks

An efficient palladium(0)-catalyzed, Cu(I)-mediated synthetic route to trisubstituted olefins and conjugate dienes has been developed via oxo directing Liebeskind-Srogl cross-coupling reactions of gem-dihaloolefin-type α-oxo ketene dithioacetals with aryl

Reduction of β-Arylthio- or β-Alkylthio-αβ-Unsaturated Ketones

The preparation and reduction of β-arylthio or β-alkylthio-αβ-unsaturated ketones (1) with lithium aluminium hydride or sodium borohydride have been examined.Reduction of the ketones (1) with lithium aluminium hydride gave αβ-unsaturated ketones (2), in which the olefinic (R1) and carbonyl (R2) substituents are reversed compared with the starting αβ-unsaturated ketone (1), or the saturated γ-hydroxy-sulphides (3).Reduction of the ketones (1) with sodium borohydride afforded only the αβ-unsaturated ketones (2).Reduction of (1) with sodium borohydride in the presence of metal halides gave the saturated ketones (5).