78084-15-8Relevant academic research and scientific papers
OXIDATION OF THE 2,16 DOUBLE BOND OF VINCADIFFORMINE
Hugel, Georgette,Laronze, Jean-Yves,Laronze, Jacqueline,Levy, Jean
, p. 581 - 590 (2007/10/02)
Chemical vs photochemical oxidation of the 2,16 double bond of vincadifformine 1 and 3-oxo vincadifformine 2 yielded inter alia, respectively the ketooexindoles 7 and 8.Attempts of partial synthesis of vincatine 15 from these derivatives were unsuccessful, The structure of the LAH reduction product of vincatine is revised to 21.The stereochemical course of an earlier total synthesis of vincadifformine is examined.
