78095-22-4

Basic information

• Product Name: α-(N-n-propyl-N-benzylamino)-3,4-dimethoxyacetophenone
• Synonyms: α-(N-n-propyl-N-benzylamino)-3,4-dimethoxyacetophenone
• CAS NO: 78095-22-4
• Molecular Weight: 327.423
• Mol File: 78095-22-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-(N-n-propyl-N-benzylamino)-3,4-dimethoxyacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: α-(N-n-propyl-N-benzylamino)-3,4-dimethoxyacetophenone(78095-22-4)
• EPA Substance Registry System: α-(N-n-propyl-N-benzylamino)-3,4-dimethoxyacetophenone(78095-22-4)

Safety Data

• Hazardous Substances Data: 78095-22-4(Hazardous Substances Data)

Upstream product

• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 2032-33-9 N-benzyl-N-propylamine 

Downstream Products

• 690618-78-1 2-n-propyl-4-(3',4'-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 78095-30-4 2-n-propyl-4-(3',4'-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide 
• 345300-37-0 N-n-propyl-N-benzyl-2-(3,4-dimethoxyphenyl)-2-hydroxyethylamine 

Relevant articles and documents

Dopamine Agonist Properties of N-Alkyl-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines

A series of homologous N-alkyl-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines was synthesized and examined for a dopamine-like ability to dilate the renal artery.The N-methyl derivative was equipotent to the 3',4'-dihydroxy derivative of the antidepressant agent nomifensine, indicating that the 8-amino group of the latter is not essential for dopamine-like activity.The N-ethyl homologue was reduced in potency when compared to the N-methyl, and the N-n-propyl, surprisingly, was essentially devoid of activity.This was unexpected in view of the fact that in all series of dopamine-like agents reported to date, N-alkylation, when one of the alkyls was an n-propyl group, either allowed retention or enhancement of potency.