781-16-8

Usage

Type of compound

Biphenyl derivative

Explanation

A biphenyl is an organic compound consisting of two phenyl rings connected by a carbon-carbon bond. 1,1'-Biphenyl, 2,2',6,6'-tetrafluoro- is a derivative of biphenyl, meaning it has a similar structure but with additional functional groups or modifications.

Explanation

The compound is a solid at room temperature, with a colorless and crystalline appearance.

Explanation

The compound does not dissolve well in water, indicating that it has limited solubility.

Explanation

The compound contains four fluorine atoms, making it a perfluorinated compound. This property can affect its chemical and physical characteristics.

Explanation

The compound serves as a starting material for the synthesis of various advanced materials and chemicals, including those used in the production of liquid crystals, polymers, and high-performance coatings. It is also used in the manufacturing of electronic components and as a heat transfer fluid in industrial applications.

Explanation

The compound can pose health risks if it is inhaled or ingested, and it may cause irritation to the skin and eyes upon contact. Proper handling and safety precautions are necessary to minimize these risks.

Physical state

Colorless, crystalline solid

Solubility

Slightly soluble in water

Fluorine content

Four fluorine atoms

Uses

Precursor for advanced materials, chemicals, liquid crystals, polymers, high-performance coatings, electronic components, and heat transfer fluid

Stability

Stable and non-flammable

Toxicity

Can be toxic when inhaled or ingested, may cause skin and eye irritation upon contact

Upstream product

• 696-62-8 para-iodoanisole 
• 35779-04-5 1-tert-butyl-4-iodobenzene 
• 552-16-9 ortho-nitrobenzoic acid 
• 385-00-2 2,6-difluorobenzoic acid 
• 133117-48-3 1,3-difluoro-2-trimethylsilylbenzene 

Downstream Products

• 19261-04-2 dibenzo[b,d]furan-1,9-diol 

Relevant academic research and scientific papers

Gold Catalyzed Decarboxylative Cross-Coupling of Iodoarenes

This report details a decarboxylative cross-coupling of (hetero)aryl carboxylates with iodoarenes in the presence of a gold catalyst (>25 examples, up to 96% yield). This reaction is site specific, which overcomes prior limitations associated with gold catalyzed oxidative coupling reactions. The reactivity of the (hetero)aryl carboxylate correlates qualitatively to the field effect parameter (Fortho). Reactions with isolated gold complexes and DFT calculations support a mechanism proceeding through oxidative addition at a gold(I) cation with decarboxylation being viable at either a gold(I) or a silver(I) species.

Synthesis of biaryls by Pd-catalyzed decarboxylative homo- and heterocoupling of substituted benzoic acids

By carefully choosing the right substrate ratio, catalyst combination, and base, symmetrical and unsymmetrical biaryls can be readily synthesized through the Pd-catalyzed decarboxylative homo- and heterocoupling of substituted benzoic acids. The reaction gave the desired products in 40-90% yield and is compatible with 2-nitro-, 2-methoxy-, 2-fluoro-, and 2-chloro-substituted benzoic acids. With the correct substrate ratio, catalyst combination, and base, symmetrical and unsymmetrical biaryls can be readily synthesized through the Pd-catalyzed decarboxylative homo- and heterocoupling of substituted benzoic acids.

Synthesis, NMR spectroscopic characterisation and reactions of 2,6-difluorophenylxenon fluoride, 2,6-F2C6H3XeF

[2,6-F2C6H3Xe][BF4] is quantitatively transferred into 2,6-F2C6H3XeF in reactions with [NMe4]F. The latter has been isolated as a colourless solid which is stable in dichloromethane solution at room temperature for approximately 1 h. 2,6-F2C6H3XeF readily reacts with Me3SiX (X = Cl, Br, CN, NCO, OCOCF3, OSO2CF3, C6F5, 2,6-F2C6H3) to give compounds of general compositions 2,6-F2C6H3XeX which were identified by multinuclear NMR experiments. Evidence was found for C6H5Xe(2,6-F2C6H3) as a product of the reaction with C6H5SiF3.