78149-65-2Relevant academic research and scientific papers
Preparation, structure, and conformation in solution of diacetyl derivatives of 6,7-dimethyl-1,4-dihydroquinoxaline and of dihydropyridotriazines
Armand, Joseph,Boulares, Line,Simonnin, Marie-Paule,Bellec, Christian,Convert, Odile,et al.
, p. 3210 - 3215 (2007/10/02)
A conformational study of 1,4-diacetyl-1,4-dihydro-6,7-dimethylquinoxaline is carried out by low temperature nmr in CD2Cl2.Important acetyl rotation induced shifts have been observed for the peri and ortho protons.These results, together with low temperature nOe experiments, permit the determination of the structures and conformations of four diacetyl derivatives of dihydropyrido as-triazines and of one diacetyl derivative of a dihydropyrido as-triazine.
Chemical and Electrochemical Reduction of Pyrido-as-triazines
Armand, J.,Chekir, K.,Ple, N.,Queguiner, G.,Simonnin, M. P.
, p. 4754 - 4759 (2007/10/02)
The catalytic hydrogenation of 3-phenylpyrido-as-triazine (1) and of 3-phenylpyrido-as-triazine (2) leads to the corresponding 1,4-dihydro derivatives 3c and 4c.The structures of these compounds were established by 1H NMR using the nuclear Overhauser effect and long-range coupling constants.Reduction by LiAlH4 gives the 5,6,7,8-tetrahydro derivative of 1 and the 4,5,6,10-tetrahydro derivative of 2; the conformation of the latter compound has been established.In aqueous methanol, 1 and 2 are electrochemically reduced into 3c and 4c, respectively; the same products are obtained in acetonitrile in the presence of phenol.The electrochemical reduction of 2 in acetonitrile in the presence of acetic anhydride leads to a mixture of 1,4-diacetyl-1,4-dihydro and 1,2-diacetyl-1,2-dihydro compounds.These results are compared with those obtained in the reduction of other azanaphthalenes.
