78157-93-4

Basic information

• Product Name: 4-(3-Carbamoyl-4,5-dioxo-2-thioxo-pyrrolidin-1-yl)-benzoic acid ethyl ester
• CAS NO: 78157-93-4
• Molecular Weight: 320.326
• Mol File: 78157-93-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3-Carbamoyl-4,5-dioxo-2-thioxo-pyrrolidin-1-yl)-benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-Carbamoyl-4,5-dioxo-2-thioxo-pyrrolidin-1-yl)-benzoic acid ethyl ester(78157-93-4)
• EPA Substance Registry System: 4-(3-Carbamoyl-4,5-dioxo-2-thioxo-pyrrolidin-1-yl)-benzoic acid ethyl ester(78157-93-4)

Safety Data

• Hazardous Substances Data: 78157-93-4(Hazardous Substances Data)

Upstream product

• 1205-06-7 4-ethoxycarbonylphenyl isothiocyanate 
• 78157-88-7 4-(3-Carboxy-2-cyano-3-oxo-thiopropionylamino)-benzoic acid ethyl ester 

Downstream Products

• 78158-00-6 4-(2-Carbamoyl-3-carboxy-3-oxo-thiopropionylamino)-benzoic acid ethyl ester 

Relevant articles and documents

INVESTIGATIONS IN THE SERIES OF ARYLHYDRAZONES OF SUBSTITUTED GLYOXYLIC ACIDS: XXVIII: ETHYL CYANOPYRUVATE IN REACTION WITH ARYL ISOTHIOCYANATES

Ethyl sodiocyanopyruvate reacts with aryl isocyanates in dimethylformamide with the formation of N-arylcyanooxalothioacetamides and 1-aryl-4-carbamoylpyrrolidine-2,3-dione-5-thione.Alkaline hydrolysis of the latter leads to opening of the pyrrolidine ring