781613-69-2Relevant academic research and scientific papers
Synthesis and biological evaluation of meperidine analogues at monoamine transporters
Lomenzo, Stacey A.,Rhoden, Jill B.,Izenwasser, Sari,Wade, Dean,Kopajtic, Theresa,Katz, Jonathan L.,Trudell, Mark L.
, p. 1336 - 1343 (2007/10/03)
A series of aryl-substituted meperidine analogues was synthesized, and the binding affinities were determined at the DAT, SERT, and NET as well as at μ-opioid receptors. Generally the analogues exhibited increased affinity for the DAT and SERT relative to
Synthesis, dopamine and serotonin transporter binding affinities of novel analogues of meperidine
Lomenzo, Stacey A.,Izenwasser, Sari,Gerdes, Robert M.,Katz, Jonathan L.,Kopajtic, Theresa,Trudell, Mark L.
, p. 3273 - 3276 (2007/10/03)
A series of meperidine analogues was synthesized and the binding affinities for the dopamine and serotonin transporters were determined. The substituents on the phenyl ring greatly influenced the potency and selectivity of these compounds for the transpor
