78164-00-8

Basic information

• Product Name: VINEOMYCINE A1
• Synonyms: 12a-alpha))-a-alph;6-beta))-5-((5,6-dihydro-6-methyl-5-oxo-2h-pyran-2-yl)oxy)tetrahydro-6-6r*);antibioticos4742a(sub1);benz(a)anthracene-1,7,12(2h)-trione,9-(2,6-dideoxy-4-o-((2s-(2-alpha,5-beta(2s;hyl-5-oxo-2h-pyran-2-yl)oxy)tetrahydro-6-methyl-2h-pyran-2-yl)oxy)-3,4,4a,12b;methyl-2h-pyran-2-yl)-beta-d-arabino-hexopyranosyl)-3-((5-((5,6-dihydro-6-met;os-4742a1;p1894b
• CAS NO: 78164-00-8
• Molecular Formula: C₄₉H₅₈O₁₈
• Molecular Weight: 934.97
• Product Categories: Antibiotic
• Mol File: 78164-00-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.45g/cm³
• Refractive Index: 1.638
• Storage Temp.: 2-8°C
• CAS DataBase Reference: VINEOMYCINE A1(CAS DataBase Reference)
• NIST Chemistry Reference: VINEOMYCINE A1(78164-00-8)
• EPA Substance Registry System: VINEOMYCINE A1(78164-00-8)

Safety Data

• WGK Germany: 3
• RTECS: CB9522000
• Hazardous Substances Data: 78164-00-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C49H58O18/c1-22-30(50)9-13-37(60-22)64-33-11-15-39(62-24(33)3)66-46-26(5)59-35(19-32(46)52)27-7-8-28-41(43(27)54)44(55)29-17-18-48(57)21-47(6,20-36(53)49(48,58)42(29)45(28)56)67-40-16-12-34(25(4)63-40)65-38-14-10-31(51)23(2)61-38/h7-10,13-14,17-18,22-26,32-35,37-40,46,52,54,57-58H,11-12,15-16,19-21H2,1-6H3/t22-,23-,24-,25-,26+,32+,33-,34-,35+,37-,38-,39-,40-,46+,47-,48-,49-/m0/s1

Upstream product

• 1444866-62-9 C₄₉H₆₆O₁₈ 

Downstream Products

• 35775-20-3 (4S,5S)-2,3,6-trideoxy-L-threo-hexose(2,4-dinitrophenyl)hydrazone 
• 51151-95-2 α-L-rhodinoside 
• 26055-63-0 aquayayamycin 
• 25019-73-2 methyl α-L-amicetoside(methyl 2,3,6-trideoxy-α-L-erythro-hexopyranoside) 
• 59492-30-7 methyl (5S)-2,3,6-trideoxy-α-L-glycero-hexopyranosid-4-ulose 
• 51013-33-3 (5S,6S)-6-methyltetrahydro-2H-pyran-2,5-diol 
• 51013-33-3 (4S,5S)-4,5-dihydroxy-hexanal (R)-1->5-cyclohemiacetal 
• 247244-65-1 L-aculose 

Relevant articles and documents

Identification of the grincamycin gene cluster unveils divergent roles for GcnQ in different hosts, tailoring the L-rhodinose moiety

The gene cluster responsible for grincamycin (GCN, 1) biosynthesis in Streptomyces lusitanus SCSIO LR32 was identified; heterologous expression of the GCN cluster in S. coelicolor M512 yielded P-1894B (1b) as a predominant product. The ΔgcnQ mutant accumulates intermediate 1a and two shunt products 2a and 3a bearing l-rhodinose for l-cinerulose A substitutions. In vitro data demonstrated that GcnQ is capable of iteratively tailoring the two l-rhodinose moieties into l-aculose moieties, supporting divergent roles of GcnQ in different hosts.