781658-89-7Relevant academic research and scientific papers
A 4′-C-ethynyl-2′,3′-dideoxynucleoside analogue highlights the role of the 3′-OH in anti-HIV active 4′-C-ethynyl- 2′-deoxy nucleosides
Siddiqui, Maqbool A.,Hughes, Stephen H.,Boyer, Paul L.,Mitsuya, Hiroaki,Van, Que N.,George, Clifford,Sarafinanos, Stefan G.,Marquez, Victor E.
, p. 5041 - 5048 (2004)
4′-C-Ethynyl-2′-deoxynucleosides belong to a novel class of nucleoside analogues endowed with potent activity against a wide spectrum of HIV viruses, including a variety of resistant clones. Although favorable selectivity indices were reported for several
