781660-26-2

Upstream product

• 1394826-60-8 tert-butyl 2-(4-cyanophenylsulfonamido)ethylcarbamate 
• 49584-26-1 p-cyanobenzenesulfonyl chloride 

Downstream Products

• 1394826-62-0 t-butyl 4-[N-(2-({diisopropoxyphosphoryl}formamido)ethyl)sulfamoyl]benzylcarbamate 
• 1394826-61-9 diisopropyl 2-(4-cyanophenylsulfonamido)ethylcarbamoylphosphonate 

Relevant academic research and scientific papers

Carbamoylphosphonates control tumor cell proliferation and dissemination by simultaneously inhibiting carbonic anhydrase IX and matrix metalloproteinase-2. Toward nontoxic chemotherapy targeting tumor microenvironment(1)

Carbamoylphosphonates (CPOs) have been identified as inhibitors of matrix metalloproteinases (MMPs) and as orally active, bioavailable, and safe antimetastatic agents. In this article, we focus on the direct antitumor activity of the CPOs. We discovered t