781668-45-9Relevant academic research and scientific papers
Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1
Nicolaou,Koftis, Theocharis V.,Vyskocil, Stepan,Petrovic, Goran,Tang, Wenjun,Frederick, Michael O.,Chen, David Y.-K.,Li, Yiwei,Ling, Taotao,Yamada, Yoichi M. A.
, p. 2859 - 2872 (2007/10/03)
The molecular structure of azaspiracid-1, a neurotoxin isolated from mussels, has been elucidated by total synthesis which also enriched its supplies. The degradatively derived fragments of this marine biotoxin, compounds 5 (EFGHI), 6 (FGHI), and 40 (ABCD
Structural revision and total synthesis of azaspiracid-1, part 1: Intelligence gathering and tentative proposal
Nicolaou,Vyskocil, Stepan,Koftis, Theocharis V.,Yamada, Yoichi M. A.,Ling, Taotao,Chen, David Y.-K.,Tang, Wenjun,Petrovic, Goran,Frederick, Michael O.,Li, Yiwei,Satake, Masayuki
, p. 4312 - 4318 (2007/10/03)
Phantom molecules from Nature: Degradation studies of azaspiracid-1 (see originally proposed, incorrect structure), the notorious marine neurotoxin isolated from contaminated mussels, revealed that the double bond of ring A was located at C7-C8 and not at
