78221-22-4

Usage

Uses

Used in Scientific Research:
CHEMBRDG-BB 4012460 is used as a building block for the synthesis of other compounds in scientific research. Its unique chemical structure allows it to be a valuable component in the development of new chemical entities.
Used in Pharmaceutical Development:
CHEMBRDG-BB 4012460 is used as a potential therapeutic agent for the treatment of inflammatory conditions. Its anti-inflammatory properties make it a promising candidate for further research and development in the pharmaceutical industry.
Used in Inflammation Treatment Research:
CHEMBRDG-BB 4012460 is being studied for its potential use in treating inflammatory conditions. Its anti-inflammatory properties are currently under investigation to determine its mechanism of action and therapeutic potential in various inflammatory diseases.

InChI:InChI=1/C9H19NO2/c1-3-5-6-8(10)7-9(11)12-4-2/h8H,3-7,10H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 80914-26-7 3-(Acetylamino)oenanthsaeure-methylester 
• 80914-15-4 N-Pentanethioyl-acetamide 
• 80914-20-1 3-Acetylamino-2-heptensaeure-methylester 
• 142342-64-1 3-[Benzyl-((R)-2-hydroxy-1-phenyl-ethyl)-amino]-heptanoic acid ethyl ester 

Relevant academic research and scientific papers

Stereoselective ring opening of chiral oxazolidines by reformatsky reagents: An enantioselective entry to β-amino esters

Chiral oxazolidines obtained by condensation of aldehydes with (-).(R)- or (+).(S)-N-benzylphenylglycinol react with the Reformatsky reagent derived from ethyl bromoacetate, in mild reaction conditions (Et2O or CH2Cl2, 0°C, 15-60 min), leading to ethyl β-amino carboxylates in moderate to good diastereomeric excess (60-92%). These ring opening products are transformed into primary β-aminoesters, in one step, by debenzylation with H2/Pd on carbon without loss of their stereochemical integrity. In this way, ethyl β-amino carboxylates can be obtained in both enantiomeric forms, with chemical yields ranging 55-76% and moderate to good e.e. (60-92%).

Thiocarbonyl Olefination, IV. - Preparation of β-Amino Acids from N-(Acetyl)thioamides; Total Synthesis of Iturinic Acid

A new method for the synthesis of β-amino acids is described whose key step consists in the regioselective thiocarbonyl olefination of N-(acetyl)thioamides with methyl (triphenylphosphoranylidene)acetate.By this procedure, a straightforward synthesis of iturinic acid has been carried out for the first time.