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1,3,7-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE, also known as triazaspirone, is a unique spiro compound characterized by its distinctive spiro skeleton structure that includes two heterocyclic rings. This chemical compound has garnered interest due to its potential pharmacological properties, particularly in the realms of anxiety and depression treatment. Triazaspirone's ability to exhibit anxiolytic and antidepressant effects without inducing sedation or altering locomotor activity positions it as a promising candidate for the development of novel therapeutic agents.

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  • 78222-09-0 Structure
  • Basic information

    1. Product Name: 1,3,7-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE
    2. Synonyms: 1,3,7-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE;1,3,7-Triaza-spiro[4.5]decane-2,4-dione HCl;1,3,7-Triaza-spiro[4.5]decane-2,4-dione hydrochloride;1,3,7-Triazaspiro[4.5]decan-2,4-dione
    3. CAS NO:78222-09-0
    4. Molecular Formula: C7H11N3O2
    5. Molecular Weight: 169.18
    6. EINECS: N/A
    7. Product Categories: pharmacetical
    8. Mol File: 78222-09-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.35 g/cm3
    6. Refractive Index: 1.578
    7. Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
    8. Solubility: N/A
    9. PKA: 10.13±0.20(Predicted)
    10. CAS DataBase Reference: 1,3,7-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1,3,7-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE(78222-09-0)
    12. EPA Substance Registry System: 1,3,7-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE(78222-09-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 78222-09-0(Hazardous Substances Data)

78222-09-0 Usage

Uses

Used in Pharmaceutical Industry:
1,3,7-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE is used as a potential anxiolytic and antidepressant agent for its demonstrated effects in preclinical studies, where it has shown to alleviate symptoms of anxiety and depression without causing sedation or affecting locomotor activity.
Further research and clinical trials are essential to explore the full potential uses and safety profile of 1,3,7-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE, ensuring its viability as a new therapeutic agent for treating anxiety and depression disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 78222-09-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,2,2 and 2 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 78222-09:
(7*7)+(6*8)+(5*2)+(4*2)+(3*2)+(2*0)+(1*9)=130
130 % 10 = 0
So 78222-09-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H11N3O2/c11-5-7(10-6(12)9-5)2-1-3-8-4-7/h8H,1-4H2,(H2,9,10,11,12)

78222-09-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3,9-triazaspiro[4.5]decane-2,4-dione

1.2 Other means of identification

Product number -
Other names 1,3,7-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:78222-09-0 SDS

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