78222-40-9Relevant articles and documents
PREPARATION OF 2S-DIOXO ISOSTERS OF N-METHYLATED ISOGUANINES
Goya, Pilar,Ochoa, Carmen,Stud, Manfred
, p. 525 - 528 (2007/10/02)
Preparation of 7-amino-3,6-dimethylimidazo-1,2,6-thiadiazine 5,5-dioxide which involves formylation of the corresponding furazanothiadiazine derivative, reductive cleavage of the furazan moiety and subsequent cyclization to the imidazole ring is described.For the synthesis of 1-methyl- and 3-methyl-7-amino-4H-imidazo-1,2,6-thiadiazine 5,5-dioxide, the corresponding 4-benzyl-imidazothiadiazine was prepared and methylated to give a mixture of the 4-benzyl-1-methyl and 4-benzyl-3-methyl isomers which were finally debenzylated by catalytic hydrogenation.The structures of the newly synthesized compounds are discussed on the basis of their spectroscopic data.