78222-45-4Relevant academic research and scientific papers
SYNTHESIS OF 2-AMINO-6-PHENYL-4(3h)-PYRIMIDINONE-1-OXIDE
Wierenga, Wendell,Skulnick, Harwey I.,Dow, Robert L.,Chidester, Constance G.
, p. 563 - 571 (2007/10/02)
Introduction of a 2,4-dichlorophenoxy group at the 4-position of 2-amino-6-phenylpyrimidine allowed a regioselective oxidation to the N1-oxide.The resultant pyrimidine oxide, derived from m-chloroperoxybenzoic acid treatment, was converted to the pyrimidinone by acidic hydrolysis.The structure was unambiguously determined by x-ray crystallographic analysis.
