78229-33-1Relevant academic research and scientific papers
Reactions with Indole Derivatives, XLII. A Stereoselective Synthesis of Tetracyclic Methylene-lactams
Ernst, Hansgeorg,Hauser, Bernhard,Winterfeldt, Ekkehard
, p. 1894 - 1906 (2007/10/02)
Tetracyclic methylene-lactams 7 of specified stereochemistry are obtained via Pictet-Spengler cyclisation and methylene-lactam rearrangement sequence.Their configuration and conformation a secured by spectroscopic data.The investigation of substitution reactions revealed smooth formation of cyclopropane derivatives (-> 15, 20).
