78246-90-9

Usage

Uses

Used in Organic Synthesis:
Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propen-1-yl)-2,2-dimethylis utilized as a synthetic intermediate for introducing cyclopropane rings and carbonyl chloride functional groups into a variety of organic compounds. Its presence allows for the creation of new molecules with distinct properties and potential applications.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propen-1-yl)-2,2-dimethylmay serve as a key building block in the development of new drugs. Its unique structural features could contribute to the design of novel therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propen-1-yl)-2,2-dimethyl- could be employed to develop new pesticides or herbicides. Its reactivity and structural attributes might enable the creation of more effective and targeted agrochemicals.
Laboratory Safety:
It is crucial to handle Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propen-1-yl)-2,2-dimethylwith care in a laboratory setting due to its reactivity and potential hazards. Proper safety measures and precautions should be taken to ensure the well-being of researchers and the integrity of experiments.

Upstream product

• 74609-46-4 3-(2-chloro-3,3,3-trifluoroprop-1-en-yl)-2,2-dimethylcyclopropanecarboxylic acid 

Downstream Products

• 68085-85-8 α-cyano-3-phenoxybenzyl-3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate 
• 82657-04-3 rel-(1R,3R)-(2-methyl[1,1'-biphenyl]-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]-2,2-dimethylcyclopropanecarboxylate 
• 1581244-68-9 C₁₇H₁₃ClF₈O₂ 

Relevant academic research and scientific papers

NOVEL CRYSTALLINE FORM OF TEFLUTHRIN, PROCESS FOR ITS PREPARATION AND USE THEREOF

Provided are the crystalline form of tefluthrin of formula (I), the crystal preparation process, the analyses of the crystal through various analytical methods and using the crystal to prepare stable agrochemical formulation. Also provided is the use of various solvents towards the crystalline form preparation conditions.

Preparation method of cyanogen chrysanthemum ester insecticide

The invention discloses a preparation method of a Clocythrin pesticide. The method comprises the following steps: a) mixing chrysanthemic acid and chrysanthemyl chloride and placing the mixture into a reaction vessel, adding triethylamine and introducing phosgene, slowly heating to 55-110 DEG C and fully reacting for 1-4 h so as to generate Chrysanthemoyl chloride; and b) dissolving sodium cyanide in an aqueous-phase Triton micellar solution, adding a catalyst and heating to 40 DEG C, slowly and dropwise adding mixed liquor of Chrysanthemoyl chloride and m-Phenoxybenzaldehyde, keeping the temperature and reacting for 1-4 h, cooling to 10 DEG C, adding a few amount of water and crystal seed, fully stirring and precipitating solids, and washing the precipitated solids with alkali, washing, filtering and drying so as to obtain a final product Clocythrin. The solvent in the invention can be recycled, use of the catalyst and water is reduced, and discharge of toxic wastewater and exhaust gas is minimized. The post-processing procedure is simple, and extraction and solvent distillation are not required. The final product can be obtained through simple centrifugation, washing and filtration. Discharge of solid wastes is decreased.

Synthesis and evaluation of a new series of substituted acyl(thio)urea and thiadiazolo [2,3-a] pyrimidine derivatives as potent inhibitors of influenza virus neuraminidase

A series of substituted acyl(thio)urea and 2H-1,2,4-thiadiazolo [2,3-a] pyrimidine derivatives were prepared and both of their cell culture and enzymatic activity toward influenza virus were tested. Their in vitro neuraminidase inhibitory activities were in good agreement with the corresponding activities in cultured cells and they were evaluated as potent neuraminidase inhibitors. Of the analogues that demonstrated IC50s 0.1 μM, 16 and 60 were further investigated as candidates with the most potential for future development. The molecular docking work of the representative compound was described to provide more insight into their mechanism of action and further rationalize the observations of this new series herein, which represents a novel class of highly potent and selective inhibitors of influenza virus.

Arthropodicidal 2,2-dimethyl-3-(2-perfluoroalkyl-2-perhaloalkyl-vinyl)-cyclopropanecarboxylic acid esters

2,2-Dimethyl-3-(2'-perfluoroalkyl-2'-perhaloalkyl-vinyl)-cyclopropane of the formula STR1 in which R is --COOR2, --COOH, --CO--Halogen, --CN or --CO--CH3, R1 is fluorine or CF3, R3 is fluorine, chlori