782479-08-7

Upstream product

• 881651-64-5 3-(2-{(S)-2-[(2R,3R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-furan-2-yl]-1-methyl-ethyl}-[1,3]dioxolan-2-yl)-1-{2-[2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-[1,3]dithian-2-yl}-propan-1-one 
• 881651-48-5 (E)-(2S,4R,7S)-8-Benzyloxy-7-methyl-oct-5-ene-1,2,4-triol 
• 881651-46-3 (E)-(S)-6-Benzyloxy-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-methyl-hex-3-en-2-one 
• 881651-47-4 (E)-(2R,5S)-6-Benzyloxy-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-methyl-hex-3-en-2-ol 
• 881651-49-6 (2S,3R,5S)-2-((1S,2R)-3-Benzyloxy-1-iodo-2-methyl-propyl)-5-hydroxymethyl-tetrahydro-furan-3-ol 
• 127929-53-7 Dimethyl (S)-4,5-Isopropylidenedioxy-2-oxopentylphosphonate 
• 881651-63-4 3-(2-{(S)-2-[(2R,3R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-furan-2-yl]-1-methyl-ethyl}-[1,3]dioxolan-2-yl)-1-{2-[2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-[1,3]dithian-2-yl}-propan-1-ol 
• 881651-52-1 (2R,3R,5S)-2-((S)-3-Benzyloxy-2-methyl-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan 
• 881651-55-4 (S)-1-[(2R,3R,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-methyl-hept-6-en-3-ol 
• 881651-56-5 (S)-1-[(2R,3R,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-methyl-hept-6-en-3-one 
• 881651-59-8 (2R,3R,5S)-2-[(S)-2-(2-But-3-enyl-[1,3]dioxolan-2-yl)-propyl]-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-3-ol 
• 881651-50-9 (2S,3R,5S)-2-((1S,2R)-3-Benzyloxy-1-iodo-2-methyl-propyl)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-3-ol 
• 881651-53-2 (S)-3-[(2R,3R,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-methyl-propan-1-ol 
• 881651-54-3 (S)-3-[(2R,3R,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-methyl-propionaldehyde 

Downstream Products

• 881652-07-9 C₄₈H₇₄O₈Si₂ 
• 881652-03-5 C₄₄H₆₈O₈Si₂ 
• 881652-12-6 C₄₄H₆₀O₁₀Si 
• 881652-08-0 C₄₂H₆₀O₈Si 
• 881652-09-1 C₄₂H₅₈O₈Si 
• 881652-04-6 C₃₉H₆₀O₇Si₂ 
• 881652-11-5 C₄₂H₅₈O₈Si 
• 881652-06-8 C₄₀H₆₀O₆Si₂ 
• 881652-10-4 C₄₂H₅₆O₈Si 
• 881652-05-7 C₃₉H₅₈O₇Si₂ 
• 881652-13-7 C₄₂H₅₈O₇Si 
• 782479-32-7 C₃₈H₅₂O₈Si 
• 881652-16-0 C₃₇H₄₈O₇Si 
• 881652-14-8 C₃₇H₅₀O₆Si 

Relevant academic research and scientific papers

Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1

The molecular structure of azaspiracid-1, a neurotoxin isolated from mussels, has been elucidated by total synthesis which also enriched its supplies. The degradatively derived fragments of this marine biotoxin, compounds 5 (EFGHI), 6 (FGHI), and 40 (ABCD

Structural revision and total synthesis of azaspiracid-1, part 2: Definition of the ABCD domain and total synthesis

The chase for the structure of azaspiracid-1 has ended with a revised structure (see picture). The total synthesis of this challenging target has closed another chapter in this intriguing chemical detective story and allowed the assignment of the relative